Symptom patterns and relative distribution of functional bowel disorders in 1,023 gastroenterology patients in Iran

Roshandel, Delnaz; Rezailashkajani, Mohammadreza; Shafaee, Sepideh; Zali, Mohammad Reza

doi:10.1007/s00384-006-0117-6

Cited by 19 publications

(32 citation statements)

References 28 publications

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“…Studies have shown that between two thirds to 100% of IBS patients may complain of bloating in Iran and worldwide (4,5,10,15). In our study, bloating was reported by 82.7% of IBS patients.…”

Section: Bloating In Other Gastrointestinal Disorderssupporting

confidence: 51%

“…This may be because unlike other symptoms, such as abdominal pain, people do not evaluate bloating as a warning symptom unless it becomes very severe. However, most patients rank bloating as a very bothersome symptom in comparison with other GI symptoms (25); it also accounts for a high percentage of referrals to gastroenterologists and causes increases in sick days and medication use (10). In this study, we reported a 184 high prevalence of bloating and FB in a sample of apparently healthy Iranian adults.…”

Section: Discussionmentioning

confidence: 54%

“…Two studies in the US (4,5), reported that bloating is seen in almost one fifth of the general population; several other studies conducted in Canada, Mexico, and Australia reported prevalences of 4.1% to 21% for FB (6)(7)(8). Previous limited studies using the Rome criteria suggest that FB has a prevalence of between 1.5% to 10% in the general population in Iran (9,10). In several Iranian studies in different selected populations, the prevalence of bloating shows a wide range of between 1.5% and 49% (11).…”

Section: Introductionmentioning

confidence: 98%

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Risk factors of bloating and its association with common gastrointestinal disorders in a sample of Iranian adults

Keshteli

Daneshpajouhnejad

Adibi³

2017

Turk J Gastroenterol

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Background/Aims: Bloating is an unpleasant but common gastrointestinal symptom that is experienced by many people at some stage in their lives. The current survey was conducted to investigate the epidemiology and risk factors of bloating and functional bloating (FB). In addition, we aimed to assess the association between bloating and functional gastrointestinal disorders (FGIDs). Materials and Methods: In this cross-sectional study, the self-administered modified Rome III questionnaire was used to assess gastrointestinal symptoms and FGIDs. Severity of bloating, demographic and anthropometric measurements, physical activity level, psychological distress, and depression and anxiety were also assessed. Results: Among the 4763 participants, 52.9% reported having experienced bloating at least occasionally in the past three months (among which 14.1% had severe or very severe symptoms); 19.7% of subjects were found to have FB. After adjusting for multiple variables, female gender, university degree, obesity, and anxiety were associated with both bloating and FB, while depression and psychological distress were only associated with bloating. The positive predictive value and negative predictive value of bloating for the diagnosis of functional bowel disorder were 92.9% and 80.1%, respectively. Conclusion: Bloating and FB are highly prevalent in the study population. We also identified several demographic, psychological, and lifestyle-related risk factors of bloating in this population. Keywords: Bloating, functional bloating, functional gastrointestinal disorders, Iran, epidemiology Original Article retention, weak anterior wall muscle tone, abnormal gut microflora, inflammation, and altered bowel tonic and phasic motility, none of these has been scientifically proven (3,14). However, studies have shown both increased intestinal gas accumulation and delayed gas transit to be important causes of bloating. Distorted perception and visceral hyperalgesia may also play a role in some patients (2,3,5,14).Physical exercise accelerates gut transit and thus reduces bloating; however, studies on healthy subjects found that physical activity accelerated gas transit but did not affect bloating. The relationship between physical activity and bloating remains unclear (5). Obesity is also an established risk factor for FGIDs; however, data regarding its effects on bloating contain discrepancies (14). Psychological therapies have also been found to be useful in improving bloating and several other FGIDs; however, it remains unclear whether an actual relationship exists between bloating and psychosocial distress (2). Studies have also evaluated the associations of bloating with smoking, marital status, age, and education level (4,5,7); however, data confirming the associations of these variables is limited.The prevalence of bloating, as a symptom, is dramatically higher in subjects who suffer from other FGIDs, notably irritable bowel syndrome (IBS) (4). Studies have shown that more than two thirds of IBS patients may complain ...

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Section: Bloating In Other Gastrointestinal Disorderssupporting

confidence: 51%

Section: Discussionmentioning

confidence: 54%

Section: Introductionmentioning

confidence: 98%

See 1 more Smart Citation

Risk factors of bloating and its association with common gastrointestinal disorders in a sample of Iranian adults

Keshteli

Daneshpajouhnejad

Adibi³

2017

Turk J Gastroenterol

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“…In Asians, IBS commonly overlaps with functional dyspepsia 19,22-26. In a population based study in India, the prevalence of dyspepsia was found to be higher in IBS patients compared to the general population 27.…”

Section: Stomachmentioning

confidence: 98%

Asian Motility Studies in Irritable Bowel Syndrome

Lee¹

2010

J Neurogastroenterol Motil

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Altered motility remains one of the important pathophysiologic factors in patients with irritable bowel syndrome (IBS) who commonly complain of abdominal pain and stool changes such as diarrhea and constipation. The prevalence of IBS has increased among Asian populations these days. Gastrointestinal (GI) physiology may vary between Asian and Western populations because of differences in diets, socio-cultural backgrounds, and genetic factors. The characteristics and differences of GI dysmotility in Asian IBS patients were reviewed. MEDLINE search work was performed including following terms, 'IBS,' 'motility,' 'transit time,' 'esophageal motility,' 'gastric motility,' 'small intestinal motility,' 'colonic motility,' 'anorectal function,' and 'gallbladder motility' and over 100 articles were categorized under 'esophagus,' 'stomach,' 'small intestine,' 'colon,' 'anorectum,' 'gallbladder,' 'transit,' 'motor pattern,' and 'effect of stressors.' Delayed gastric emptying, slow tansit in constipation predominant IBS patients, rapid transit in diarrhea predominant IBS patients, accelerated motility responses to various stressors such as meals, mental stress, or corticotrophin releasing hormones, and altered rectal compliance and altered rectal accomodation were reported in many Asian studies regarding IBS. Many conflicting results were found among these studies and there are still controversies to conclude these as unique features of Asian IBS patients. Multinational and multicenter studies are needed to be performed vigorously in order to elaborate characteristics as well as differences of altered motililty in Asian patients with IBS.

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“…It was reported that patients with diarrhea had a wide variety of symptoms [24]. The symptom of loose, mushy or watery stools was the most frequent symptom of functional diarrhea.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Functional Diarrhea and Comparison with Diarrhea-Predominant Irritable Bowel Syndrome: A Population-Based Survey in China

Zhao

Guo

Zhang³

et al. 2012

PLoS ONE

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BackgroundThe epidemiology of functional diarrhea and its impacts on Chinese remain unclear, and there are no data on the comparative epidemiology of functional diarrhea and diarrhea-predominant irritable bowel syndrome (IBS-D). This study was to explore the epidemiology of functional diarrhea and its impacts, and to identify its distinction from IBS-D.Methods and FindingsA cross-sectional survey was conducted in 16078 respondents, who were interviewed under a randomized stratified multi-stage sampling design in five cities of China. All respondents completed the modified Rome II questionnaire, and the 36-item Short Form health survey (SF-36) was used for assessing health-related quality of life in 20% of the sample. Overall, 248 respondents (1.54%) had functional diarrhea and 277 (1.72%) had IBS-D. Functional diarrhea was positively associated with increasing age and body mass index (trend test P<0.05). The three most common symptoms for at least 3 weeks in the past months were loose, mushy or watery stools (n = 203, 81.85%), more than three bowel movements a day (n = 100, 40.32%) and having to rush to the toilet to have a bowel movement (n = 72, 29.03%). Meaningful impairment was observed in 5 of the 8 SF-36 domains in respondents with functional diarrhea. The demographics are mostly similar between the respondents with functional diarrhea and IBS-D; however, respondents with IBS-D had more frequent symptoms of diarrhea and even lower scores in SF-36 domains than those with functional diarrhea.ConclusionsThe prevalence of functional diarrhea in China is substantially lower than that in Western countries and relatively higher than that in other Asian countries. It impaired health-related quality of life, and respondents with IBS-D have even worse quality of life. Further population-based studies are needed to investigate the epidemiology of functional diarrhea and the differences between functional diarrhea and IBS-D.

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Symptom patterns and relative distribution of functional bowel disorders in 1,023 gastroenterology patients in Iran

Abstract: Population-based studies at provincial levels are essential to clarify FBD patterns in each provincial district in the country.

Cited by 19 publications

References 28 publications

Risk factors of bloating and its association with common gastrointestinal disorders in a sample of Iranian adults

Risk factors of bloating and its association with common gastrointestinal disorders in a sample of Iranian adults

Asian Motility Studies in Irritable Bowel Syndrome

Epidemiology of Functional Diarrhea and Comparison with Diarrhea-Predominant Irritable Bowel Syndrome: A Population-Based Survey in China

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