Synchronous Diffuse Large B-Cell Lymphoma and Malignant Clonal Plasma Cells in Bone Marrow As Primary Presentation: A Diagnostic and Therapeutic Challenge

Synchronous Presentation of Two Extranodal Lymphomas: Follicular Lymphoma and Extranodal Marginal Zone Lymphoma of the Mucosa-Associated Lymphoid Tissue (MALToma)

“…The most commonly reported double malignancies are solid tumors with hematological neoplasms, such as gastric cancer with diffuse large B-cell lymphoma (DLBCL), lung adenocarcinoma with chronic myeloid leukemia, colon cancer with myeloma, and lung cancer with myeloma [3]. However, synchronous presentation of two hematologic neoplasms is extremely rare and reported generally as myeloproliferative diseases (MPDs) with lymphoproliferative diseases [3], and the combinations were as follows: concomitant histiocytic sarcoma and DLBCL [4], DLBCL with myeloma [5], mantle cell lymphoma with chronic lymphocytic leukemia (CLL) [6,7], and DLBCL with Hodgkin's lymphoma [8,9], MPDs with CLL, and MPDs with hairy cell leukemia [10].…”