Synchrotron Radiation X‐ray Imaging in Biomedical Research

Wang, Liping; Yang, Guo‐Yuan; Xu, Lisa X.

doi:10.1002/9783527697106.ch16

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2022

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“…High-resolution X-ray tomographic microscopy is one of the most powerful and sought-after 3D full field imaging methods for micro-scale structural investigations of virtually any material [1][2][3][4][5][6]. Thanks to the high flux of synchrotron radiation sources, high-quality measurements can be collected in a matter of minutes or even seconds, allowing for high throughput or time-resolved observations of the microstructure and its evolution in a sample [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of a fractal pattern device for focus characterizations of X-ray imaging systems by Si deep reactive ion etching and bottom-up Au electroplating

et al. 2022

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Precisely aligned optical components are crucial prerequisites for X-ray tomography at high resolution. We propose a device with a fractal pattern for precise automatic focusing. The device is etched in a Si substrate by deep reactive ion etching and then filled by a self-terminating bottom-up Au electroplating process. The fractal nature of the device produces an X-ray transmission image with globally homogeneous macroscopic visibility and high local contrast for pixel sizes in the range of 0.165 µm to 11 µm, while the high absorption contrast provided between Au and Si enables its use for X-ray energies ranging from 12 keV to 40 keV.

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