Synergism between electricity and ionizing radiation

There is interest in the use of photodynamic therapy for the treatment of certain diseases, including cancer. However, weak penetration of visible light in tissues has restricted its use. In this study the possibility of enhancing photodynamic effects by the use of energies that penetrate more deeply in tissues was investigated. Weak electric currents (1.0 mA) applied to Escherichia coli cells for short periods, producing little or no lethal damage, was found to act synergistically with the photodynamic action of methylene blue, significantly enhancing the effects of this treatment. This synergism exists also between electrolysis and X-rays but not between electrolysis and UV-254 nm. It is suggested that this synergism might eventually be used to improve the results obtained in therapeutic practice based on the utilization of photodynamic action.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Synergism between electricity and ionizing radiation

Cited by 5 publications

References 18 publications

Combination therapy: Photochemotherapy; electric current; and ionizing radiation. Different combinations studied in a WiDr human colon adenocarcinoma cell line

Combination therapy: Photochemotherapy; electric current; and ionizing radiation. Different combinations studied in a WiDr human colon adenocarcinoma cell line

Mycotoxins, fungus and ‘electrohypersensitivity’

Synergism between Electrolysis and Methylene Blue Photodynamic Action inEscherichia Coli

Contact Info

Product

Resources

About