1995
DOI: 10.1016/0730-725x(94)00119-n
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Synovial thickening detected by MR imaging in osteoarthritis of the knee confirmed by biopsy as synovitis

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Cited by 183 publications
(120 citation statements)
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“…The importance of synovitis in OA progression is well recognized 32e36 . OA knee joints usually show signs of synovitis, even in the early stage of the disease 37,38 . MR imaging in patients who either have or are at risk for knee OA showed that high-grade synovitis was associated with knee pain compared with those with no or lowgrade synovitis 39,40 .…”
Section: Discussionmentioning
confidence: 99%
“…The importance of synovitis in OA progression is well recognized 32e36 . OA knee joints usually show signs of synovitis, even in the early stage of the disease 37,38 . MR imaging in patients who either have or are at risk for knee OA showed that high-grade synovitis was associated with knee pain compared with those with no or lowgrade synovitis 39,40 .…”
Section: Discussionmentioning
confidence: 99%
“…Although present in low numbers, B cells and plasma cells were detected in OA ST 8,9,11,29,34,35,44 . However, their relative abundance is lower than in RA 44 .…”
Section: B Cellsmentioning
confidence: 97%
“…Several authors reported that macrophages and T cells are the most abundant cells 8,9,11,17,20,21,25,34,35,37,45,47,48,51,56,57,61,62,69,78 . Mast cells (MCs) 49,50,54,55,58e60,64,67,70,79 , as well as B cells and plasma cells were found, although the last two in lower amounts than other cells 9,11,21,24,25,33e35,44,45,57,69,73 .…”
mentioning
confidence: 99%
“…In a human data series, some degree of synovial thickening was found in a majority of osteoarthritic joints (Fernandez-Madrid et al 1995). Whether this synovitis contributes directly to articular cartilage loss in OA, or simply arises in reaction to the breakdown of cartilage, remains unclear.…”
Section: Synovitis and Joint Effusionsmentioning
confidence: 99%