Synthesis and characterization of hydroxyapatite-based coatings for medical implants obtained on chemically modified Ti6Al4V substrates

Formation of hydroxyapatite coatings with addition of chitosan from aqueous solutions by thermal substrate method

“…The thermal substrate method for obtaining of HA coatings based on the main principle that the solubility of HA in aqueous solutions decreases with increasing substrate temperature [2,24]. Alternating current passed through the system to heat the substrate.…”

“…By this method hydroxyapatite directly coated the substrate without precipitation in the initial solution. The experimental arrangement for coating deposition is described in the work [24].…”

“…Among methods for HA-CS coating deposition are simple mixing and heating method [13], biomimetic method [14][15][16], low temperature wet chemical method [17], electrochemical deposition [18], electrochemistry assisted deposition [19,20], electrophoretic deposition [21,22]. In our work we proposed thermal substrate method [23,24] (TSM) for deposition of F HA-CS coatings onto Ti 6 Al 4 V substrates from aqueous solutions. The main advantage of this method is a thermal activation near substrate surface which immersed in aqueous solutions containing Ca 2+ and PO 4 3-for hydroxyapatite synthesis with promoted crystallization and formation of film-like deposits [24].…”

“…In our work we proposed thermal substrate method [23,24] (TSM) for deposition of F HA-CS coatings onto Ti 6 Al 4 V substrates from aqueous solutions. The main advantage of this method is a thermal activation near substrate surface which immersed in aqueous solutions containing Ca 2+ and PO 4 3-for hydroxyapatite synthesis with promoted crystallization and formation of film-like deposits [24]. Several factors influence the HA nucleation and crystallization: chitosan concentration in the initial solution, pH value of the solution, Ca 2+ and PO 4 3-ion concentrations, the heating time and temperature, substrate surface modification, etc.…”

Enhancing the Properties of Ti6Al4V as a Biomedical Material: A Review

“…Results also reveal that the cell proliferation of Collagen/Ca-P was significantly higher than those of the other specimen. Another study on various types of chemical pretreatment with NaOH, HF, or H 2 O 2 to form bioactive hydroxyapatite (HA) coatings by a thermal substrate method has been reported [42]. This method has proved suitable for a rapid formation of uniform coatings on titanium and Ti 6 Al 4 V substrates at low temperatures, having chemical composition and film thickness under control.…”