Synthesis and characterization of water-soluble O-carboxymethyl glucomannan derivatives

An, Nguyễn Tiến; Đông, Nguyễn Thị; Dung, Pham Le; Thiện, Đỗ Trường

doi:10.1016/j.carbpol.2010.08.034

Cited by 22 publications

(7 citation statements)

References 11 publications

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“…In brief, AL (5 g) was dissolved in 100 mL deionized water with a little NaOH at 50 °C and the pH was adjusted to 3–5. The 30% H 2 O 2 of 2 mL/g lignin and FeSO 4 (16 mM) were added in the solution and the mixture was reacted at room temperature (22 ± 1 °C) and 80 rpm in a water bath for 24 h. Carboxylated Lignin (CL) was prepared through the reaction between hydroxyl groups and sodium chloroacetate, as described previously [ 39 ]. The solution of AL was mixed with sodium chloroacetate of 4 mol/L at the ratio of 2:1.…”

Section: Methodsmentioning

confidence: 99%

Effect of alkaline lignin modification on cellulase–lignin interactions and enzymatic saccharification yield

Ying

Shi

Yang

et al. 2018

Biotechnol Biofuels

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BackgroundThe lignin can compete for binding cellulase enzymes with cellulose fibers and decrease the accessibility of enzymes to carbohydrates. The competitive adsorption of cellulase to lignin mainly depended on the chemical structure of lignin. The post-pretreatment can decrease the lignin content and modify the lignin structure of pretreated substrates, which reduced the lignin inhibition on enzymatic saccharification. Therefore, the post-treatment by modifying the lignin structure would attract considerable attention for weakening the cellulase–lignin interactions.ResultsThree modified lignins, including sulfonated lignin (SL), oxidized lignin (OL), and carboxylated lignin (CL), were prepared from alkali lignin (AL) and their structures and physicochemical properties were characterized using FTIR, NMR, XPS analysis, zeta potential, and contact angle, respectively. Compared to AL, three modified lignin preparations exhibited the decrease in contact angle by 61–70% and phenolic hydroxyls content by 17–80%, and an obvious increase of negative charges by about 21–45%. This was mainly due to the drop of condensation degree and the incorporation of carboxylic and sulfonic acid groups into modified lignins. Langmuir adsorption isotherms showed that the affinity strength between cellulase and modified lignins significantly reduced by 54–80%. Therefore, the 72 h hydrolysis yield of Avicel with SL, OL, and CL was 48.5, 51.3, and 49.4%, respectively, which was increased 8–15.3% than that of Avicel with AL, 44.5%. In the enzymatic hydrolysis of bamboo biomass, the glucose yield at 5 d was 38.5% for AS-P. amarus, 15.4% for AO-P. amarus and 21.4% for AC-P. amarus, respectively, which were 1.4–3.5 times of alkali pretreated P. amarus.ConclusionsThe post-treatment can weaken the nonproductive adsorption between lignin and cellulase proteins and improve the enzymatic saccharification efficiency. This study will provide a conceptual combination of pretreatment technologies and post-pretreatment by modifying lignin structure for reducing the cellulase–lignin interaction.

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Section: Methodsmentioning

confidence: 99%

Effect of alkaline lignin modification on cellulase–lignin interactions and enzymatic saccharification yield

Ying

Shi

Yang

et al. 2018

Biotechnol Biofuels

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“…27,28 Briefly, 100 mg of Mannan from Saccharomyces cerevisiae were dissolved in 1 mL of DI water and 1 mL of 1 M NaOH was added dropwise with constant stirring while the solution was kept in an ice bath. After 30 min, 1 mL of a 20% w/v chloroacetic acid solution were subsequently added dropwise, and then the mixture was allowed to react at 60 °C for 6 h with constant stirring.…”

Section: Methodsmentioning

confidence: 99%

Surface-Modified P(HEMA-co-MAA) Nanogel Carriers for Oral Vaccine Delivery: Design, Characterization, and In Vitro Targeting Evaluation

et al. 2014

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Oral drug delivery is a route of choice for vaccine administration because of its noninvasive nature and thus efforts have focused on efficient delivery of vaccine antigens to mucosal sites. An effective oral vaccine delivery system must protect the antigen from degradation upon mucosal delivery, penetrate mucosal barriers, and control the release of the antigen and costimulatory and immunomodulatory agents to specific immune cells (i.e., APCs). In this paper, mannan-modified pH-responsive P(HEMA-co-MAA) nanogels were synthesized and assessed as carriers for oral vaccination. The nanogels showed pH-sensitive properties, entrapping and protecting the loaded cargo at low pH values, and triggered protein release after switching to intestinal pH values. Surface decoration with mannan as carbohydrate moieties resulted in enhanced internalization by macrophages as well as increasing the expression of relevant costimulatory molecules. These findings indicate that mannan-modified P(HEMA-co-MAA) nanogels are a promising approach to a more efficacious oral vaccination regimen.

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“…Low viscosity glucomannan (LGM) has glucomannan levels of 25.93%, while high viscosity glucomannan (HGM) contain 21.41% of glucomannan. CMGM was synthesized from glucomannan following the procedure described by An et al (An et al, 2011). The addition of NaOH during carboxymethylation reaction at an elevated temperature of 60 °C, can trigger the hydration of glucomannan.…”

Section: Results and Discussion Synthesis Of Carboxymethyl Glucomannanmentioning

confidence: 99%

“…The synthesis of CMGM was following the procedure described by An et al (2011) with minor modifications. A gram of each glucomannan powder, was dissolved in 100 mL distilled water and mixed with a magnetic stirrer.…”

Section: Synthesis Of Carboxymethyl Glucomannanmentioning

confidence: 99%

“…Carboxymethyl glucomannan (CMGM) is one of glucomannan derivatives, produced from the reaction between glucomannan and monochloroacetate, using NaOH as a catalyst (An, Dong, Dung, & Thien, 2011;Kobayashi, Tsujihata, Hibi, & Tsukamoto, 2002;Wang, Zhu, Xu, Qiao, & Zhang, 2011). CMGM has desirable characteristics suitable for a metal biosorbent.…”

Section: Introductionmentioning

confidence: 99%

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Carboxymethyl Glucomannan from Amorphophallus oncophyllus as an Alternative Heavy Metal Removal from Wastewater: Adsorption of Cadmium and Zinc

Hikmat

Resdiana²,

Tasfiyati

2021

Molekul

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Carboxymethyl glucomannan (CMGM) was successfully synthesized through the reaction of glucomannan from Amorphophallus oncophyllus and monochloroacetic acid, using NaOH as a catalyst. Two types of glucomannan were used in this study, low viscosity glucomannan (LGM) and high viscosity glucomannan (HGM). The produced CMGM were differentiated into LCMGM (synthesized from LGM) and HCMGM (synthesized from HGM). The CMGM structure was characterized by FTIR, and the degree of substitution (DS) was determined using back titration method. The DS value were 0.484 and 0.412 for LCMGM and HCMGM, respectively. Both CMGMs were then evaluated for its adsorption capacity towards Zn and Cd at the optimum pH of 6, with 60 minutes adsorption time for each sample. The maximum adsorption capacity of Zn was 13.61 mg/g and 13.04 mg/g for LCMGM and HCMGM, respectively. While for Cd, the maximum adsorption capacity of LCMGM and HCMGM was 17.70 mg/g and 15.90 mg/g. The adsorption capacity of the sample follows the Langmuir isotherm adsorption. In conclusion, CMGM from A. oncophyllus has demonstrated its potential as a reusable adsorbent for efficient removal of Cd and Zn.

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Synthesis and characterization of water-soluble O-carboxymethyl glucomannan derivatives

Cited by 22 publications

References 11 publications

Effect of alkaline lignin modification on cellulase–lignin interactions and enzymatic saccharification yield

Effect of alkaline lignin modification on cellulase–lignin interactions and enzymatic saccharification yield

Surface-Modified P(HEMA-co-MAA) Nanogel Carriers for Oral Vaccine Delivery: Design, Characterization, and In Vitro Targeting Evaluation

Carboxymethyl Glucomannan from Amorphophallus oncophyllus as an Alternative Heavy Metal Removal from Wastewater: Adsorption of Cadmium and Zinc

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