2018
DOI: 10.3390/polym10090991
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Synthesis and in Vitro Cytocompatibility of Segmented Poly(Ester-Urethane)s and Poly(Ester-Urea-Urethane)s for Bone Tissue Engineering

Abstract: Two series of segmented polyurethanes were obtained and their mechanical and thermal properties as well as their biodegradability and cytotoxicity were evaluated. The chemical nature of the polyurethanes was varied by using either 1,4 butanediol (poly-ester-urethanes, PEUs) or l-lysine ethyl ester dihydrochloride (poly-ester-urea-urethanes, PEUUs) as chain extenders. Results showed that varying the hard segment influenced the thermal and mechanical properties of the obtained polymers. PEUs showed strain and ha… Show more

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Cited by 19 publications
(15 citation statements)
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“…Biocompatibility is a critical element in the evaluation of a biomaterial [ 32 , 33 ]. The cell viabilities result (Fig.…”
Section: Discussionmentioning
confidence: 99%
“…Biocompatibility is a critical element in the evaluation of a biomaterial [ 32 , 33 ]. The cell viabilities result (Fig.…”
Section: Discussionmentioning
confidence: 99%
“…Biocompatibility is a critical element in the evaluation of a biomaterial which determines the final destination of the biomaterials [5,41]. There are various factors influencing the biocompatibility, such as pH and the product of degradation.…”
Section: Discussionmentioning
confidence: 99%
“…16 PCL is one of the most extensively used biodegradable polyesters, due to the fact that the degradation product of PCL is 6-hydroxyhexanoic acid, which is naturally metabolized by the human body. 17 o-Dianisidine (3,3 0 -dimethoxybenzidine) we used it in these syntheses as chain extender. Until now, odianisidine was used to obtain soluble polyphenol derivatives containing azomethine groups, 18 conjugated aromatic polyazomethine, 19 poly(azomethine-urethane), 20 in synthesis of phenol Schiff bases, 21 as accelerator in the curing process of benzoxazine based bisphenol Aaniline, 22 in synthesis of poly (keto-amine).…”
Section: Introductionmentioning
confidence: 99%