Synthesis and Insecticidal Activity of Some 1,3,4‐Oxadiazole Derivatives Containing Phenoxyfluorophenyl Group.

Abstract

Group. -Along with their synthesis, the results of studies on the insecticidal activity of a few new oxadiazole derivatives, e.g. (III), are reported. (IIIb) and (IIIc) show low insecticidal activity against A. craccivora. -(MOHAN, T. P.; VISHALAKSHI*, B.; BHAT, K. S.; RAO, K. S.; KENDAPPA, G. N.; Indian J.

Design, synthesis, insecticidal activity and 3D-QSR study for novel trifluoromethyl pyridine derivatives containing an 1,3,4-oxadiazole moiety

“…[10][11][12][13][14][15][16] Such as sulfoxaor, a representative commercial insecticide, and was industrialized by Dow Agroscience. 16 1,3,4-Oxadiazole derivative is a highly active pharmacophore and widely was used in pesticide molecules, 17 many active substance containing such a scaffold have been reported as insecticides, [18][19][20][21][22][23][24] fungicides, [25][26][27][28][29][30][31] and herbicides, 32-34 some of them were treated as a pesticide candidate for further industrialization. 25 Recently, Liu and co-workers reported the 1,3,4-oxadiazole derivative with an anthranilic diamide moiety possessed excellent insecticidal activity against P. xylostella, 20 as well as some insecticidal sarisan analogues with an 1,3,4-oxadiazole scaffold were developed by Guo et al 23,35 And in our recent work, a series of insecticidal 1,3,4-oxadiazole molecules bearing a 3-chloropyridin-2-yl-1H-pyrazole was proposed.…”

“…Structures of the compounds E1 to E28 were established on basis of 1 H NMR, 19 F NMR, 13 C NMR and HR-MS data. In the 1 H NMR spectra, the H proton near the "N" of pyridine appeared as a singlet near d 8.95 ppm.…”

Synthesis and Characterization of 1,3,4-Oxadiazoles Derivatives from 1,2,3,4-Tetrahydroisoquinoline and their Bioevalution (Antibacterial & Antifungal)

“…1,3,4-Oxadiazole was found to possess a wide spectrum of pharmacological activity such as antibacterial [3][4] , anti fungal [5][6] , anthelminitic 7 , anti tubercular 8 , anti-infective 9 , anti cancer 10 , anti-HIV 11 , anti oxidant 12 , analgesic [13][14] , anti histanamic 15 , insectivdal 16 , anti-inflammatory 17 , and anti convulsant [18][19] .…”

Antibacterial and Enzyme Inhibition Screening of Some New Acetamide and Azomethine Derivatives

“…The molecules bearing heterocyclic 1,3,4-Oxadiazole ring [1][2][3][4] , acetamoyl moiety [5][6][7][8][9] and azomethine moiety [10][11][12][13] have been demonstrated to exhibit a wide spectrum of pharmacological activities including anticancer, antimicrobial, antidepressant, anti-inflammatory, antioxidant, anticonvulsant and many other activities. We have introduced different molecules possessing multiple functionalities [14][15][16][17] along with remarkable antibacterial and antienzymatic activities.…”