Synthesis and molecular structure of 2,4,8a-triaryl-6-methylperhydro[1,3,2]dioxaborinino[5,4-c]pyridines

Organo-boron compounds S 0040Synthesis and Molecular Structure of 2,4,8a-Triaryl-6-methylperhydro[1,3,2]dioxaborinino[5,4-c]pyridines. -Condensation of 1,3-diol (I) with arylboronic acids affords the title compounds (III), which are representatives of a new heterocyclic system. Their stereochemistry and molecular structures are established by single crystal X-ray diffraction analysis. -(LE TUAN ANH; POLYANSKII, K. B.; ANDRESYUK, A. N.; SOLDATENKOV*, A. T.; MAMYRBEKOVA, Z. A.; KULESHOVA, L. N.; KHRUSTALEV, V. N.; Russ. Chem. Bull. 53 (2004) 4, 842-845; Russ. Peoples' Friendship Univ., Moscow 117198, Russia; Eng.) -D. Singer 03-165

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Synthesis and Molecular Structure of 2,4,8a‐Triaryl‐6‐methylperhydro[1,3,2]dioxaborinino[5,4‐c]pyridines.

Anh

Polyanskii

Andresyuk

et al. 2004

ChemInform

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The investigation of structure–activity relationship of polyamine-targeted synthetic compounds from different chemical groups

et al. 2019

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Screening of Some Dioxaboreninopyridine and Aniline Derivatives for Carcinogenic Properties Using a Model Cell-Free System of Regenerating Rat Liver

et al. 2017

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We studied the effects of some aniline and dioxaborininopyridine derivatives on the rate of oxidative deamination of putrescine and polyamines in a tissue with high mitotic index. These effects were evaluated quantitatively by measuring diamine oxidase and polyamine oxidase activities in a model cell-free test system of regenerating rat liver tissue. Aniline derivatives exhibited mainly antiproliferative effects and promoted oxidative degradation of putrescine, spermidine, and spermine. Dioxaborininopyridine derivatives inhibited this process, thus exhibiting carcinogenic properties.

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Synthesis and molecular structure of 2,4,8a-triaryl-6-methylperhydro[1,3,2]dioxaborinino[5,4-c]pyridines

Cited by 3 publications

References 3 publications