Abstract:cal properties of the synthesized 2-aminothiazoles are summarized in Table II. Some derivatives of 2-aminothiazoles were prepared by the method of Shriner et al. ( 12) and are listed in Table II.
The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed. Their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophiles, alkenes, and alkynes are discussed.
The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed. Their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophiles, alkenes, and alkynes are discussed.
“…A general synthetic route for 4-aryl-1,2,3,4-tetrahydroisoquinolines 166 was reported from the reaction of aromatic aldehydes 163, methyl amine and α-haloacetophenones in the presence of sodium borohydride followed by cyclization with sulfuric acid and zinc in methanol (Scheme 47) [362][363][364][365]. Several pyrazines [373][374][375][376][377][378][379][380][381], oxazines [382][383][384][385], and thiazines [386][387][388][389][390][391][392][393] were obtained when 177 were treated with α-haloketones (Scheme 51).…”
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