Synthesis and Thermophysical Properties of Biocompatible Cholinium-Based Amino Acid Ionic Liquids

Abstract

Nowadays the knowledge of thermodynamic properties for amino acid ionic liquids (AAILs) has been paramount for the design of many chemical processes. In this present work, a series of cholinium-based AAILs ([Ch][AA]) were synthesized by neutralization of choline hydroxide solution with five amino acids and then were characterized by 1 H NMR, Fourier transform infrared (FT-IR), elemental analysis, thermogravimetry, and differential scanning calorimetry (DSC) analysis. Physico-chemical properties such as density, viscosity, refractive index, and conductivity were measured and correlated with the empirical equations in a wide temperature range. The thermal expansion coefficient values were also calculated from the acquired experimental density values. From the experimental data, it was found that the density, viscosity, and refractive index decreased while conductivity increased with the increase of temperature. The correlation results were proposed to be in good agreement with the experimental data, and optimal fitting parameters were presented. In addition, the coefficient of thermal expansion was considered to be independent of temperature in the range of (298.15 to 353.15) K.

Thermophysical properties and acute toxicity towards green algae and Vibrio fischeri of amino acid-based ionic liquids

“…T s values for the AAILs are within 490-509 K, which are comparable to other AAILs reported earlier [26,38]. All the AAILs in this work have good thermal stability N 473.15 K at a scan rate of 10°C · min −1 .…”

Cholinium-amino acid based ionic liquids: a new method of synthesis and physico-chemical characterization

“…11 They reported the values of T g and T d and the temperature dependence of viscosity (η), density (ρ), conductivity (σ) and refractive index (n D ). Comparing data of these two manuscripts important differences between some [Ch] [ [Ser] reported in the two manuscripts are completely different (more than one order of magnitude).…”

Aggregation behavior of non-cytotoxic ester functionalized morpholinium based ionic liquids in aqueous media

“…The investigations on aggregation behavior of SAILs have gained momentum in the recent times. Numerous SAILs based on a variety of cationic head groups such as pyridinium [15], imidazolium [16], morpholinium [17], amino acids [18] and pyrrolidinium [19], have been synthesized, characterized and investigated for their aggregation behavior. These SAILs have been found to self-assemble where characteristic properties of aggregates depend on the nature of the solvent and nature of the constituent ions of SAILs.…”