Synthesis and X‐Ray Crystal Structure of 3‐Oxo‐23,24‐dinorchol‐4‐ene‐22‐cyanohydrin.

Abstract

Steroids Steroids U 0300Synthesis and X-Ray Crystal Structure of 3-Oxo-23,24-dinorchol-4-ene-22-cyanohydrin. -The synthesis of title compounds (III) and (IV) is given. The mixture of epimers is separated by preparative HPLC and the crystal structure of the (22R)-compound is determined by X-ray analysis. -(COX*, P. J.; NAHAR, L.; SARKER, S. D.; TURNER, A. B.; J. Chem. Res., Synop. 2004, 3, 192-193; Sch. Pharm., Robert Gordon Univ., Aberdeen AB9 1FR, UK; Eng.) -H. Haber 39-165