Synthesis, Characterisation and Antiamoebic Studies of Dioxovanadium(<scp>V</scp>) Complexes Containing ONS Donor Ligands Derived from <i>S</i>‐Benzyldithiocarbazate

Maurya, Mannar R.; Khurana, Shilpa; Shailendra,; Azam, Amir; Zhang, Wenjian; Rehder, Dieter

doi:10.1002/ejic.200200642

Cited by 71 publications

(33 citation statements)

References 38 publications

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“…They show features similar to those observed for other mono-or dinuclear pervanadyl species; [41] in addition a band at 1588 cm Ϫ1 may be assigned as ν(CϪC) of the phenyl ring, [42,43] and a very sharp band at 1113 for 4a and 1117 cm Ϫ1 for 5a is due to an in-plane deformation of the phenyl ring δ(CϪH), with some ν(SiϪC) character. Consistently with the structural data (vide supra) and the existence of short VϭO bonds, there are strong ν(VϭO) bands at ca.…”

Section: Main Features Of Vibrational Studies Of Synthesised Complexesmentioning

confidence: 58%

Vanadium‐Catalysed Aerobic Cleavage of C−C Bonds in Substituted Cyclohexanones To Afford Carboxylic Acids: Two Model Complexes with Tetrahedral Geometry around Vanadium(V)

et al. 2003

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Section: Main Features Of Vibrational Studies Of Synthesised Complexesmentioning

confidence: 58%

Vanadium‐Catalysed Aerobic Cleavage of C−C Bonds in Substituted Cyclohexanones To Afford Carboxylic Acids: Two Model Complexes with Tetrahedral Geometry around Vanadium(V)

et al. 2003

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“…Thermogravimetry shows the loss of one H 2 O molecule (4.1 %) at 130 8C, which is typical for vanadyl complexes containing an equatorially coordinated aqua ligand. [25] The first ligand is degraded between 240 and 380 8C, the second around 500 8C. The overall weight loss due to ligand degradation amounts to 69.7 %, that is, part of the picolinate ligands (corresponding to 4H, 2O, and 1N) remains on vanadium, which is recovered in the form of [NH 4 ][VO 3 ].…”

Section: Resultsmentioning

confidence: 99%

A New Family of Insulin‐Mimetic Vanadium Complexes Derived from 5‐Carboalkoxypicolinates

Gätjens¹,

Meier²,

Kiss³

et al. 2003

Chemistry A European J

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The reaction of 5-carboalkoxypicolinic acid (5 ROpicH, R=Me, Et, iPr, sBu; 1 a-d) with vanadyl sulfate yielded the complexes [VO(H(2)O)(5 ROpic)(2)], 2 a-d, with H(2)O and one of the picolinato ligands in the equatorial positions, and the second picolinate occupying equatorial (N) and axial (O) positions. Reaction of 1 a with [NH(4)][VO(3)] yielded [NH(4)][VO(2)(5 MeOpic)(2)], [NH(4)]-3, in which the N functions of the picolinates are trans to the doubly bonded, cis-positioned oxo groups. Complexes 1 a.H(2)O, 1 b, 1 c, 2 a.3.5 H(2)O and [NH(4)]-3.4 H(2)O have been structurally characterised. A detailed pH-potentiometric solution speciation analysis of the system VO(2+)-1 a revealed a dominance of VO(5 OMepic)(2) between pH 2 and 6, with the same coordination pattern, evidenced by EPR spectroscopy, as in the crystalline solid state. In ternary systems containing physiological concentrations of the low molecular mass biogenic binders (B) lactate, oxalate, citrate or phosphate, ternary species of general composition VO(5 MeOpic)B dominate at physiological pH, with citrate being the most effective competitor for picolinate. All of the complexes trigger glucose uptake and degradation by simian virus modified mice fibroblasts at non-toxic concentrations (<100 microM), with 2 a, [VO(2)(pic)(2)](-) and [VO(2)(dipic)](-) being at least as effective as insulin. Vanadium uptake by the cells is most effective in the case of 2 a. 2 a also effectively inhibits free fatty acid release by rat adipocytes treated with epinephrine, thus mimicking the inhibition of lipolysis by insulin.

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“…The coordination chemistry of S-methyl-and S-benzyl dithiocarbazate Schiff bases derived from o-hydroxy aldehydes and ketones as well as a-N-heterocyclic aldehydes and ketones has been extensively studied [1][2][3][4]. Less attention, however, has been paid to Schiff bases obtained from the condensation of S-methyl-or S-benzyl dithiocarbazate with diacetylmonoxime [5,6].…”

Section: Introductionmentioning

confidence: 98%

Complexes of a diacetylmonoxime Schiff base of S-methyldithiocarbazate (H2damsm) with Fe(III), Ru(III)/Ru(II), and V(IV); catalytic activity and X-ray crystal structure of [Fe(Hdamsm)2]NO3·H2O

El‐Hendawy

Fayed

Mostafa

2011

Transition Met Chem

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The complexes [M(Hdamsm) 2 ]XÁH 2 O (M = Fe, X = NO 3 ; M = Ru, X = Cl), [Ru(Hdamsm)(PPh 3 ) 2 X 0 ] (X 0 = Cl, Br), and [VO(Hdamsm)(acac)] (H 2 damsm = diacetylmonoxime Schiff base of S-methyldithiocarbazate, Hacac = acetylacetone) have been prepared and characterized by spectroscopic techniques. Their redox properties were investigated by cyclic voltammetry. The X-ray crystal structure of [Fe(Hdamsm) 2 ]NO 3 .H 2 O has been determined and shows that the complex has a distorted octahedral geometry in which the Hdamsm behaves as a monoanionic NNS tridentate ligand coordinating via oxime nitrogen, hydrazinic imine nitrogen, and thiolate sulfur. The reactivity of these complexes toward oxidation of alcohols in the presence of t-BuOOH and H 2 O 2 as co-oxidants is reported.

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Synthesis, Characterisation and Antiamoebic Studies of Dioxovanadium(V) Complexes Containing ONS Donor Ligands Derived from S‐Benzyldithiocarbazate

Cited by 71 publications

References 38 publications

Vanadium‐Catalysed Aerobic Cleavage of C−C Bonds in Substituted Cyclohexanones To Afford Carboxylic Acids: Two Model Complexes with Tetrahedral Geometry around Vanadium(V)

Vanadium‐Catalysed Aerobic Cleavage of C−C Bonds in Substituted Cyclohexanones To Afford Carboxylic Acids: Two Model Complexes with Tetrahedral Geometry around Vanadium(V)

A New Family of Insulin‐Mimetic Vanadium Complexes Derived from 5‐Carboalkoxypicolinates

Complexes of a diacetylmonoxime Schiff base of S-methyldithiocarbazate (H2damsm) with Fe(III), Ru(III)/Ru(II), and V(IV); catalytic activity and X-ray crystal structure of [Fe(Hdamsm)2]NO3·H2O

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