Synthesis, Characterisation and Antimicrobial Evaluation of Chalcone Coupled Biscoumarin Copolyesters

Kandaswamy, Narendran

doi:10.1007/s13233-019-7082-8

Cited by 12 publications

(7 citation statements)

References 16 publications

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“…The methylene protons are observed in the range of 2.5-2.7 ppm. NMR result confirms the successful formation of the polymer PGCC and shows consistent results with literature [37][38][39].…”

Section: Resultssupporting

confidence: 90%

Photocrosslinking Property of Certain Synthesized Bis(arylidene)cycloalkanone based Random Copolyesters with Computational Support and their Anticancer Study

Kiruba

Chidambaravinayagam

2022

J. Sci. Res.

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The synthesis of random copolyesters involves polycondensation of arylidene diol with curcumin and glutaryl chloride in 1:1:2 ratio. For this monomers, 2,6-bis-(4-hydroxy benzylidene) cyclohexanone, 2,6-bis-(4-hydroxy-3-methoxybenzylidene)cyclohexanone, 2,5-bis-(4-hydroxybenzylidene)cyclopentanone and 2,5-bis-(4-hydroxy-3-methoxy benzylidene)cyclopentanone were synthesized using acid catalyzed Claisen-Schmidt reaction. Qualitative solubility tests reveal that prepared copolyesters dissolve well in polar solvents. The successful formation of copolyesters was confirmed by Fourier transform-infrared spectroscopy and proton nuclear magnetic resonance spectroscopic techniques. Glass transition temperature of prepared polymers was calculated using differential scanning calorimetric analysis. Further, the prepared copolyesters were utilized as in vitro anticancer agents against breast cancer MCF7 cells. The experimental results of phototcrosslinking property of the copolyesters was compared with that of computational method by DFT calculations which shows coincidence of both.

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“…The methylene protons are observed in the range of 2.5-2.7 ppm. NMR result confirms the successful formation of the polymer PGCC and shows consistent results with literature [37][38][39].…”

Section: Resultssupporting

confidence: 90%

Photocrosslinking Property of Certain Synthesized Bis(arylidene)cycloalkanone based Random Copolyesters with Computational Support and their Anticancer Study

Kiruba

Chidambaravinayagam

2022

J. Sci. Res.

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“…26 The copolyester shows distinctive carbonyl stretching absorption bands of the ester group near 1760 cm -1 , substantiating the presence of ester linkages in the polyester. The band near 1230 cm -1 (ester C-O stretching) also validates the presence of ester moieties in the polymer sample, as reported by Kandaswamy, N. 27 The broad detectable band around 3469 cm -1 , due to hydroxyl group stretching vibration, is also observed. 28 Bands occurring below 866 cm -1 reveal C-H bending vibrations and the aromatic ring stretch is illustrated by absorption at 1608 cm -1 and 1496 cm -1 in the FTIR spectrum.…”

Section: Ftir Spectrumsupporting

confidence: 84%

Synthesis and Studies on Aromatic Copolyester With Anticancer Activity Derived From 4,4’- Dihydroxybiphenyl and 3,5-Dihydroxytoluene

Sivaramakrishnan¹,

Elango²

2021

RJC

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In this investigation, a new wholly aromatic random copolyester containing 4,4'-dihydroxybiphenyl, 3,5dihydroxytoluene and Isophthaloyl chloride was synthesized using the solution polycondensation methodology in the mole ratio 2:1:3 and its solubility along with inherent viscosity were determined. The chemical structure of the copolyester was established by traditional spectroscopic techniques. The physical parameters of the polyester were studied employing WAXD studies and the thermal stability along with phase transitions were investigated employing TGA and DSC data. The morphological features in the polyester were probed using Scanning Electron Microscopy. The anticancer activity of copolyester was verified using HeLa (Cervical carcinoma) cell line employing MTT assay.

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“…Chalcones are compounds containing α,β unsaturated carbonyl system which are extensively explored as biologically active compounds 1–7 . The α,β unsaturated bond in chalcones can undergo 2 + 2 cycloaddition on exposure to UV irradiation 8–13 which is explored in applications require in situ crosslinking.…”

Section: Introductionmentioning

confidence: 99%

Polychalcones based on triphenylamine and carbazole building blocks via Claisen–Schmidt route

Jayalakshmi

Keerthika

Santhanagopal

2021

J of Applied Polymer Sci

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Alternating and random copolymers of carbazole and triphenylamine containing polychalcones are prepared by adopting simple Claisen–Schmidt route via A2 + B2 approach. Terephthaldehyde derivative was used as an additional comonomer along with bisaldehyde of triphenylamine to obtain a random copolymer. The prepared polymers are readily soluble in common organic solvents and the polymers exhibited narrow poly dispersity. The polymers are thermally stable and no observable degradation is observed until 350°C. Further, the spin cast thermally annealed films on glass substrate indicated corrugated surface as measured by scanning electron microscope and atomic force microscopy, which could facilitate for greater interaction at the interfaces. Photophysical properties of the polymers in solution and in thin film showed excellent emission characteristics. Both alternating and random copolymers showed a high quantum yield of 0.74 on comparison with quinine sulfate. Polychalcones with triphenylamine/carbazole showed oxidative response in cyclic voltammetry which suggested the suitability as electrochemical sensors and antioxidant coating material.

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Synthesis, Characterisation and Antimicrobial Evaluation of Chalcone Coupled Biscoumarin Copolyesters

Cited by 12 publications

References 16 publications

Photocrosslinking Property of Certain Synthesized Bis(arylidene)cycloalkanone based Random Copolyesters with Computational Support and their Anticancer Study

Photocrosslinking Property of Certain Synthesized Bis(arylidene)cycloalkanone based Random Copolyesters with Computational Support and their Anticancer Study

Synthesis and Studies on Aromatic Copolyester With Anticancer Activity Derived From 4,4’- Dihydroxybiphenyl and 3,5-Dihydroxytoluene

Polychalcones based on triphenylamine and carbazole building blocks via Claisen–Schmidt route

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