Synthesis, Characterisation, Crystal Structure, and Antimicrobial and Larvicidal Studies of [Cu(2,2′-bipy)₂SO₄]·3CH₄N₂O·2H₂O

Abstract

A pentacoordinated mononuclear copper(II) complex, namely, bis(2,2′-bipyridine)sulphatecopper(II) urea trisolvate dihydrate, has been synthesised and characterised by molar conductance and UV-Vis and FTIR spectra. The structure of the complex was unambiguously confirmed by single crystal XRD. The complex crystallizes in monoclinic system, space groupC2/c, with the valuesa = 20.155(4),b = 20.858(4), andc = 14.425(3) Å;α = 90.00°,β = 96.51°, andγ = 90.00°;V = 6025(2) Å3andZ = 8. The Cu(II) ion is coordinated to four nitrogen atoms of two bidentate 2,2′-bipyridine ligands (bipy) and by one oxygen atom of the sulphate group and displays distorted trigonal bipyramidal geometry. The crystal packing is stabilized by inter- and intramolecular hydrogen bonding. The Cu(II) complex was screened for antimicrobial activity againstStaphylococcus aureus,Escherichia coli,Klebsiella pneumonia,Aspergillus niger,Aspergillus flavus, andCandida albicans. Larvicidal activity of the synthesized copper(II) complex was carried out against larvae ofCulex quinquefasciatusandAnopheles subpictus.

Crystal structure and Hirshfeld surface analysis of (μ-2-{4-[(carboxylatomethyl)carbamoyl]benzamido}acetato-κ2 O:O′)bis[bis(1,10-phenanthroline-κ2 N,N′)copper(II)] dinitrate N,N′-(1,4-phenylenedicarbonyl)diglycine monosolvate octahydrate

“…The sum of the bond angles O1- ], O1-Cu-N4 [103.88 (12) ] and N2- ] in the equatorial plane amounts to 359.47 , indicating only slight distortions. Distances and angles within the distorted trigonalbipyramidal coordination sphere of the Cu II ion are similar to those found in the literature (Santha Lakshmi & Samundeeswari, 2015;Lim et al 2014). The nearly identical bond lengths of the carboxylate group in the bridging ligand [C30-O1 = 1.249 (5) and C30-O2 = 1.249 (6) Å ] indicate a delocalized bonding arrangement, rather than localized single and double bonds as in the case of the carboxylic group of the neutral N,N 0 -(1,4-phenylenedicarbonyl)diglycine solvent molecule [C36-O4 = 1.205 (6) and C36-O5 = 1.316 (5) Å ].…”