Synthesis, characterization, and antibacterial activity of metal complexes of phenylthiourea: the X-ray single crystal structure of [Zn(SC(NH2)NHC6H5)2(OOCCH3)2] · C2H5OH

Ajibade, Peter A.; Zulu, Nonkululeko H.

doi:10.1080/00958972.2010.510558

Cited by 14 publications

(7 citation statements)

References 28 publications

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“…In the region 3450–3100 cm −1 , the N–H vibrations that appear as a broad peak at 3450 cm −1 in the spectrum of the ligand shifted to higher wave numbers in the complexes. These shifts might be attributed to the S→M bond and increase in the C–N bonds [21,27,28]. The band at about 1480 cm −1 in the ligand shifted to about 1486–1524 cm −1 in the spectra of the complexes.…”

Section: Resultsmentioning

confidence: 99%

“…In the search for novel therapy, recent research [11–14] has demonstrated that attaching organic drugs to metal containing fragments can enhance their activity. As part of our studies [15–21] to develop metal based therapeutic agents, we report the synthesis, characterization and antimicrobial screening of metal complexes of diisopropylthiourea.…”

Section: Introductionmentioning

confidence: 99%

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Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies

Ajibade

Zulu

2011

IJMS

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Co(II), Cu(II), Zn(II) and Fe(III) complexes of diisopropylthiourea have been synthesized and characterized by elemental analyses, molar conductivity, magnetic susceptibility, FTIR and electronic spectroscopy. The compounds are non-electrolytes in solution and spectroscopic data of the complexes are consistent with 4-coordinate geometry for the metal(II) complexes and six coordinate octahedral for Fe(III) complex. The complexes were screened for their antibacterial activities against six bacteria: Escherichia coli, Pseudomonas auriginosa, Klebsiella pneumoniae, Bacillus cereus, Staphylococcus aureus and Bacillus pumilus. The complexes showed varied antibacterial activities and their minimum inhibitory concentrations (MICs) were determined.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies

Ajibade

Zulu

2011

IJMS

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“…In this case, the X-ray penetrates through the materials, and a number of particles can be expected to be oriented in such a way as to fulfill the Bragg's law. Almost all crystalline compounds analysis rely on XRD spectra, such as analysis of metal complexes of metal-thiourea and metal phenyl-thiourea [60,61] after several steps of synthesis, to determine the coordination sphere on the metal Zn(II), Co(II) and Cu(II) and the possible crystal structures. More study of the spectra confirmed the shape of crystalline compounds together with UV-Visible and infrared as well as magnetic susceptibility measurement.…”

Section: Methods For Chalcogen Materials Characterizationmentioning

confidence: 99%

“…Bulk characterization by IR was employed to analyze synthetic compounds to prove the presence of thionyl vibrational mode (ν(C-S)) with frequency band shifts to lower values after coordination with metallic atoms [66]. Similar recording of infrared spectra were found in metal complexes of thiourea and phenylthiourea crystals [60,61]. The C-H stretching of the components overlapped with N-H stretching of the thiourea, but both can be differentiated since N-H is not directly involved in bond formation with the metals.…”

Section: Methods For Chalcogen Materials Characterizationmentioning

confidence: 99%

Modern Analytical Chemistry Methods for Chalcogen Materials Analysis and Characterization

Wonorahardjo¹,

Fariati²,

Dasna³

2019

Chalcogen Chemistry

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Analytical methods are needed to elucidate modern and complex compounds as well as to describe their physical properties. The underlying principles of chalcogen chemistry as well as the natural abundance of chalcogen elements are the base of building many biological substances, including sophisticated materials for future applications. Thus, the need for modern and state-of-the art analytical methods and techniques to characterize them, is obvious. In this chapter, challenges in analytical methods for chalcogen compounds and materials, as well as some examples of natural or synthesized materials or their combinations, including biomaterials, are discussed. Modern methods for chalcogen compounds analysis and structural determination discussed include: UV-Visible and infrared spectroscopy (UV-Vis and IR), thermo analysis, electrochemistry, magnetic analysis, chromatography, X-ray methods (mostly XRF, XRD, and EDX), high-resolution microscopy (SEM and TEM), multinuclear NMR, computational analysis, and bioassay. Also, the historical background and nature of chalcogen elements, including reactivity and magnetic properties as well as thermal behavior, common compounds of chalcogen elements: organic and inorganic materials, complex chalcogen materials, will be briefly discussed.

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“…In the electronic spectra of regular tetrahedral Cu(II) complexes, a single broad band of 10 2 molar absorptivity located near the IR region is usually observed while Cu(II) complexes in square planar geometries normally show two bands in the visible regions [40]. The Cu(II) complexes showed very broad bands at 450 nm and another band of low intensity at about 640 nm.…”

Section: Electronic Spectra Of Metal Complexesmentioning

confidence: 99%

Synthesis, characterization and antibacterial studies of metal complexes of sulfadiazine with N-alkyl-N-phenyldithiocarbamate

Ajibade

Idemudia²,

Okoh³

2012

Bull. Chem. Soc. Eth.

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ABSTRACT. Co(II), Cu(II), Pd(II) and Pt(II) complexes of 4-amino-N-(2-pyrimidinyl)benzene sulfonamide (sulfadiazine) with some N-alkyl-N-phenyl dithiocarbamate have been synthesized and characterized by elemental analysis, conductivity measurements, UV-Vis and FTIR spectroscopy. The complexes are formulated as four coordinate MN2S2 species in which the metal ions are coordinated to one molecule of sulfadiazine through the pyrimidinyl and sulfulnamido nitrogen atoms and one molecule of dithiocarbamate through two sulfur atoms with both molecules acting as bidentate chelating ligands. The in vitro antibacterial activities of the complexes and sulfadiazine were evaluated against eight bacteria strains using the agar well diffusion method. The metal complexes showed varied antibacterial properties and their minimum inhibitory concentration (MIC) and maximum bactericidal concentration (MBC) were determined.

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Synthesis, characterization, and antibacterial activity of metal complexes of phenylthiourea: the X-ray single crystal structure of [Zn(SC(NH₂)NHC₆H₅)₂(OOCCH₃)₂] · C₂H₅OH

Cited by 14 publications

References 28 publications

Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies

Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies

Modern Analytical Chemistry Methods for Chalcogen Materials Analysis and Characterization

Synthesis, characterization and antibacterial studies of metal complexes of sulfadiazine with N-alkyl-N-phenyldithiocarbamate

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