Synthesis, characterization and antibacterial studies of some new tellurated azo compounds

Al-Fregi, Adil A.; Al-Salami, Bushra K; Al-Khazragie, Zainab K.; Al‐Rubaie, Ali Z.

doi:10.1080/10426507.2018.1470179

Cited by 15 publications

(4 citation statements)

References 16 publications

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“…It was proven that the molar conductance of organic mercuric compounds 1 – 3 , aryl tellurium trihalides 4 – 6 and 16 – 21 , and the dihalides 7 – 9 and 22 – 27 behaved as for 1:1 electrolytes, which are in good agreement with the previous works in DMSO [ 11 , 12 , 19 , 20 ]. These observations may be due to the ionic character of Hg–Cl and one of the Te–halide bonds in these compounds.…”

Section: Resultssupporting

confidence: 89%

“…To the best of our knowledge, through a literature search of SciFinder Scholar and Web of Knowledge, there have been few reported studies related to the synthesis of organotellurium compounds derived from pyrazoles [ 6 , 7 ]. Furthermore, due to the high significant antimicrobial activity of both pyrazoles [ 2 , 4 ] and organic tellurium compounds [ 8 , 9 , 10 ], in addition, to our interest in the field of organic synthesis for tellurium compounds by the transmetalation reactions between aryl mercury chlorides with tellurium tetrabromide [ 11 , 12 ], in the present work, we synthesized some organic tellurium compounds based on pyrazole and evaluated their microbial activity against four different bacteria.…”

Section: Introductionmentioning

confidence: 99%

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Synthesis and Antimicrobial Evaluation of Some New Organic Tellurium Compounds Based on Pyrazole Derivatives

2020

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A novel series of organic tellurium compounds based on pyrazole derivatives with a general formula of ArTeBr3 and Ar2TeBr2 [Ar = 2-(3-(4-substituted phenyl)-5-(2-chlorophenyl)-1H-pyrazol-1-yl)-3,5-dinitrophenyl] were obtained by the refluxing of corresponding aryl mercuric chlorides with TeBr4 in two different mole ratio of 1:1 and 2:1, respectively, in free-moisture dioxane solvent under an argon atmosphere. Compounds of ArTeBr3 and Ar2TeBr2 were reduced by the action of ethanolic solution of hydrazine hydrate obtained Ar2Te2 and Ar2Te, respectively. Reaction of Ar2Te2 with excess thionyl chloride or iodine gave the corresponding trihalides ArTeCl3 and ArTeI3, respectively while the reaction of Ar2Te with thionyl chloride or iodine gave the corresponding Ar2TeCl3 and Ar2TeI3, respectively. The structures were elucidated according to their elemental analysis of carbon, hydrogen and nitrogen (CHN) and some of the spectroscopic techniques such as infrared IR and nuclear magnetic resonance for 1H and 13C. The antimicrobial activity for all the synthetic compounds were assayed against both Gram-negative and Gram-positive bacteria by using the agar diffusion method. The tellurated pyrazole derivatives showed a good degree against bacteria growth. In some cases, the antimicrobial activities of the synthetic compounds were better than amoxicillin.

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Section: Resultssupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Synthesis and Antimicrobial Evaluation of Some New Organic Tellurium Compounds Based on Pyrazole Derivatives

2020

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“…Adil A. Al-Fregi et al [ 73 ], in a recent paper, synthesized a series of new azobenzene compounds complexed with tellurium and mercury ( Figure 21 ).…”

Section: Antimicrobial Organometallic Azo Compoundsmentioning

confidence: 99%

Azobenzene as Antimicrobial Molecules

et al. 2022

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Azo molecules, characterized by the presence of a -N=N- double bond, are widely used in various fields due to their sensitivity to external stimuli, ch as light. The emergence of bacterial resistance has pushed research towards designing new antimicrobial molecules that are more efficient than those currently in use. Many authors have attempted to exploit the antimicrobial activity of azobenzene and to utilize their photoisomerization for selective control of the bioactivities of antimicrobial molecules, which is necessary for antibacterial therapy. This review will provide a systematic and consequential approach to coupling azobenzene moiety with active antimicrobial molecules and drugs, including small and large organic molecules, such as peptides. A selection of significant cutting-edge articles collected in recent years has been discussed, based on the structural pattern and antimicrobial performance, focusing especially on the photoactivity of azobenzene and the design of smart materials as the most targeted and desirable application.

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“…35 Additionally, they also exhibit anti-fungal 36 and anti-bacterial properties. 37 However, to date, very few reports exist on the applications of tellurium ligated metal complexes in the catalysis of organic transformations. 17…”

Section: Introductionmentioning

confidence: 99%

Metal-metalloid bond containing complexes of the bulky organotellurium ligand: applications in catalysis of C–O coupling and aldehyde to amide transformation reactions

et al. 2023

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Synthesis, characterization and antibacterial studies of some new tellurated azo compounds

Cited by 15 publications

References 16 publications

Synthesis and Antimicrobial Evaluation of Some New Organic Tellurium Compounds Based on Pyrazole Derivatives

Synthesis and Antimicrobial Evaluation of Some New Organic Tellurium Compounds Based on Pyrazole Derivatives

Azobenzene as Antimicrobial Molecules

Metal-metalloid bond containing complexes of the bulky organotellurium ligand: applications in catalysis of C–O coupling and aldehyde to amide transformation reactions

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