Synthesis, Characterization and Antimicrobial Activities of Five and Six Member Cyclic Imides Derivatives

Synthesis, characterization and in vitro antimicrobial activity of cyclic imide: Isoindoline-1, 3-dione derivatives

“…Due to hydrophobicity and neutral structures, these compounds can easily cross biological membranes in vivo [3][4][5]. In view of the favourable pharmacokinetic properties, derivatives of cyclic imides have been found to exhibit wide range of biological activities such as antibacterial [6][7][8], antifungal [9,10], antiviral [11,12], analgesic [13,14], antiangiogenic [15,16], anti-HIV [17][18][19], antimalarial [20], anticancer [21,22], androgen receptor antagonistic [23], anti-inflammatory [24][25][26], anxiolytic [27,28], anti-depressive [29], anticonvulsant [30,31], hypolipidemic [32] and muscle-relaxant activities [33] etc.…”