Synthesis, Characterization and Antimicrobial Activity of Heterocyclic Azodyes Derived from Thiadiazole

Abstract

5-Ethyl-1,3,4-thiadiazole-2-amine have been synthesized by single step reaction. A series of heterocyclic azodyes were synthesized by coupling 8-hydroxyquinoline, 2,6-diaminopyridine, N,N-dimethyl aniline, 2-napthol and resorcinol with diazotized 5-ethyl-1,3,4-thiadiazol-2-amine in nitrosyl sulphuric acid. These dyes were characterized by UV, IR, 1 H NMR, 13 C NMR, elemental analysis and mass spectrometry for selected dyes. The synthesized compounds were also screened for biological activity.