Synthesis, characterization and antimicrobial activity of novel 2,5-substituted aryl-7-phenyl-1,3,4-oxadiazolo-[3,2-a]-1,3,5-triazine derivatives

Basedia, Deepak Kumar; Shrivastava, Birendra; Dubey, Bidhyut Kumar; Sharma, Pankaj Kumar

doi:10.7439/ijbr.v5i1.434

Cited by 10 publications

(8 citation statements)

References 21 publications

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“…The 13 C-NMR spectrum of compounds [2] and [4] showed the signal at (168-174) ppm for carbonyl group while the aromatic carbon appeared at (104-114) ppm as shown in Figure (10) and (12).…”

Section: Genaral Procedures Preparation Of Poly (N-acryl-n-sub or Unsmentioning

confidence: 99%

“…The second step: included the of preparation new five polyimides (6-10) that were prepared by the reaction of amides (1)(2)(3)(4)(5) in the first step with polyacryloyl chloride subjected to another nucleophili substitution by treating with poly acryloyl chloride using triethyl amine (Et 3 N) as catalyst. The mechanism of reaction involves a nucleophilic attach on the carbonyl as shown in Schemes (3) [14].…”

Section: Genaral Procedures Preparation Of Poly (N-acryl-n-sub or Unsmentioning

confidence: 99%

“…Triazine derivatives are used in pharmaceutical industry as coupling agents for the synthesis of peptides and as side chain of antibiotics , as well as in formulating bactericides and fungicides [1][2].…”

Section: Introductionmentioning

confidence: 99%

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Synthesis of Polyimides derived from 2,6-diamino-4-methyl-1,3,5-triazine

Journal¹

2016

Baghdad Sci.J

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This work included synthesis of several new polymers of polyacryloyl chloride in two steps . The first step the included the reaction of N-( sub. or un sub. benzoyl and sub. or un sub. acetyl ) amidyl sub. 2,6- diamino -4-methyl-1,3,5-triazine (1-5) by condensation of many substituted acid chlorides with 2,6- diamino -4-methyl-1,3,5-triazine . While the second step included the reaction of polyacryloyl chloride with the produced compounds (1-5) in step (1) in the presence amount triethyl amine (Et3N) to obtain new polyimides (6-10). The prepared compounds were characterized by UV. , FT-IR, and some of them by 1H-NMR and 13C- NMR spectroscopy.

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“…The 13 C-NMR spectrum of compounds [2] and [4] showed the signal at (168-174) ppm for carbonyl group while the aromatic carbon appeared at (104-114) ppm as shown in Figure (10) and (12).…”

Section: Genaral Procedures Preparation Of Poly (N-acryl-n-sub or Unsmentioning

confidence: 99%

Section: Genaral Procedures Preparation Of Poly (N-acryl-n-sub or Unsmentioning

confidence: 99%

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Synthesis of Polyimides derived from 2,6-diamino-4-methyl-1,3,5-triazine

Journal¹

2016

Baghdad Sci.J

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“…The derivatives of 1,2,3trazine have widely interested many researchers due to their spectrum applications in the fields of herbicides [2], drugs and catalysis in polymers [3][4][5]. The chelating triazine Lewisbases represent an important class of complex-compound due to their potential to be biologically active and mainly have been known to be antiprotozoals [6][7][8]. Hoog and co-workers [9] have investigated an-efficient synthesis of a novel class of multidentate polynucleating ligands through the substitution reaction of 2,4,6-trichloro-1,3,5-trazine.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Structural Investigation of Some Transition Metals Complexes of Benzimidazolium Bromide

2019

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The present work involves the synthesis of novel imidazolium salts of bromide in step-wise reactions which are started from preparation of 2,4-dimorpholine-6-(1H-benzimidazole-1-yl)-1,3,5-triazine (1) in potassium hydroxide and DMF solvent followed by substitution reactions with n-butyl bromide and n-octyl bromide to afford the new ligands names L1 = 1-(2,4-dimorpholino-1,3,5-triazine-2-yl)-3-butyl-1H-benzimidazol-3-ium bromide and L2 = 1-(2,4-dimorpholino-1,3,5-triazine-2-yl)-3-octyl-1Hbenimidazol-3-ium bromide. The new ligands were recrystallized from hot chloroform and the following of reactions completion were carried out by thin layer chromatography (TLC). The formula and structures of the two salts of benzimidazolium bromide were confirmed on the basis of measurements of (CHN) elemental analyses, FT-IR, NMR and EIMS spectroscopy. Furthermore the manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II) complexes were synthesized from the direct reactions of their hydrated metal salts in methanol with the solutions of the ligands in chloroform in 1:1 mole ratio and the analytical data of atomic absorption spectroscopy and elemental analyses revealed the proposed formula of the solid metal complexes. The data obtained from FT-IR, UV-Visible spectra, molar conductivity and magnetic susceptibility measurements confirmed the octahedral environment around cobalt(II) ion in [CoL(H2O)2Cl2] and the tetrahedral geometry was adopted for manganese(II) and zinc(II) ions. However the square-planner structure was expected for the copper(II) and nickel(II) complexes in [MLCl2], M = Ni(II) and Cu(II) ions and L = L1 and L2 ligands. As well as the suitable and favourable active sites in the two ligands L1 and L2 were the two nitrogen atoms of morpholine rings which has been observed from FT-IR spectra and the kinetic stability of five-member ring up on chelation with the metal ions supported the conclusion of the symmetry.

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“…In the area of this group of compounds particularly interesting seems to be 1,3,4‐oxadiazole and 1,3,4‐thiadiazole derivatives. These non‐naturally occurring compounds exhibit a broad range of biological activities and therefore are widely used in medicine and agriculture . Oxadiazole and thiadiazole derivatives have attracted attention of scientists because of their precious optical properties .…”

Section: Introductionmentioning

confidence: 99%