Synthesis, Characterization and Antioxidant Activity of Novel 3-(2,5-dioxo-imidazolidin-1-yl)-1,1-diethylurea Derivatives

Abstract

A novel class of hydantoin derivatives was synthesized and their antioxidant activity was evaluated. The newly synthesized compounds were characterized using 1 H NMR, IR, Mass spectra and elemental analysis. The antioxidant activity of synthesized compounds (3a-d) were examined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide hydroxyl radical scavenging assay. It is revealed from the antioxidant screening results that the compounds 3a and 3d manifested profound antioxidant potential.