Synthesis ,Characterization and Antioxidant Activity of Schiff base derivatives from [6,6'-(1,4-phenylene)bis(4-(4-aminophenyl) pyrimidin)]

Abstract

Two Hetreterocyclic compounds prepared from condensation reaction of Bis chalcone([3,3(1,4-phenylene)bis(1(4-aminophenyl)prop-2-en-1-one]with thiourea and urea By condensing a novel six-member heterocyclic (pyrimidene ring) with the suitable aromatic, new substituted azomethines of (o, m, and p) hydroxybenzaldehyde with heterocyclic substituents were created. By using NMR and FTIR spectroscopy, the novel heterocyclic compounds and these derivatives of schiff bases were identified.A DPPH free radical scavenging assay was performed on the synthesized compounds, and the heterocyclic substituted thiol group and its Schiff base derivative demonstrated remarkable antioxidant activity.