Synthesis, Characterization and Biological Activities of New Schiff Base Compound and Its Lanthanide Complexes

Abstract

The thermal condensation of 3-(2-Furyl)acrolein with 2-Amino-6-ethoxybenzothiazole generated a new Schiff base, (1E,2E)-N-(6-ethoxybenzo[d]thiazol-2-yl)-3-(furan-2-yl)prop-2-en-1-imine (L), with general formula of C16H14N2O2S. Also, a series of lanthanide complexes of gadolinium, samarium, and neodymium (La–Lc) were synthesized utilizing acetonitrile as the solvent and triethylamine as a buffer and catalyst. Based on elemental analysis, mass spectroscopy, and FTIR analysis, all of the Bis-(1E,2E)-N-(6-ethoxybenzo[d]thiazol-2-yl)-3-(furan-2-yl)prop-2-en-1-iminetri-nitratolanthanide(III) complexes with the general formula [LnL2(NO3)3]·H2O are solids with a 2:1 molar ratio (ligand: metal). Based on conductivity estimates, they are nonelectrolytes and monoatomic paramagnetic according to the magnetic moment measurements, and one mole of lattice water was found after thermal gravimetric measurements and FTIR analysis. Therefore, the lanthanide complexes show a ten-coordination structure with a deformed bicapped square antiprismatic. The Schiff base and its complexes were screened for their antimicrobial, antifungal, antioxidant, and antitumor properties. Their antimicrobial and antifungal activities were strong, and they also produced good antioxidant and antitumor effects.

Rapid adsorption of some heavy metals using extracted chitosan anchored with new aldehyde to form a schiff base

“…Aromatic aldehyde derivatives are fundamental intermediates that are widely utilized for the synthesis of important materials [7]. Schiff base are compounds with an azomethine group that arise as the result of a reversible acid-catalyzed condensation reaction between primary amine and carbonyl compounds, as described by Hugo Schiff in 1864 [8].…”

Synthesis and Biological Evaluation of Thiazole-Based Derivatives with Potential against Breast Cancer and Antimicrobial Agents

“…Thus, it is clear that all pure ligands act as N-donor and S-donor ligands. In the case of L2 and L3, the coordination appears through the sulfur atom from the thiazole ring and the nitrogen atom from the piperazine ring [ 24 ]. L2 and L3 ligands act as bidentate.…”

Reversible trans-to-cis photoisomerization and irreversible photocyclization reactions of a Co-coordinated stilbene derivative on chiral di-β-diketonate lanthanide complexes

“…Lanthanide complexes have a wide range of applications in analytical chemistry, catalysis, medicine, and materials. 1–21 The development of lanthanide complexes with multi-output properties by external stimulation, especially with reversible output, is of great significance in the field of smart materials. 22–26 Of the various external stimuli, such light energy, electrical energy, and chemical energy, light is a clean energy stimulus source that has the characteristics of independent changeable modality, precise control, low energy, environmental benignity, and remote control.…”