Synthesis, characterization and biological evaluation of chitosan film incorporated with β-Carotene loaded starch nanocrystals

Hari, Neethu; Francis, Stegiya; Nair, Alakananda G. Rajendran; Nair, A. Jayakumaran

doi:10.1016/j.fpsl.2018.02.003

Cited by 57 publications

(18 citation statements)

References 27 publications

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“…The prepared Chi-Ag-NPs exhibiting antioxidant activity may be considered as proton-donators due to their primary amino and hydroxyl groups. It is also stated that the free amino and hydroxyl groups of chitosan has potential to react with free radicals which leads to form highly stable ammonium and molecular radical free groups [29].…”

Section: Diphenyl-1-picryl Hydrazyl Activity (Dpph) Assaymentioning

confidence: 99%

Synthesis and biochemical characterization of silver nanoparticles grafted chitosan (Chi-Ag-NPs): in vitro studies on antioxidant and antibacterial applications

Dara

Mahadevan

Digita³

et al. 2020

SN Appl. Sci.

108

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Metal-based nanoparticles with potential antioxidant and antimicrobial properties have led to their incorporation of biomaterials for human health care importance. The present investigation is to study on the silver nanoparticles grafted chitosan (Chi-Ag-NPs) composite materials due to their potential applications. Chi-Ag-NPs were synthesized by chemical reduction of silver nitrate salts and biodegradable chitosan. The obtained Chi-Ag-NPs were characterised for Fouriertransform infrared spectroscopy (FTIR), scanning electron microscope (SEM), Transmission electron microscopy (TEM), X-ray powder diffraction, antioxidant and antibacterial properties. UV-visible spectra showed the configuration proficiency of Ag-NPs and chitosan. FTIR spectra indicated that the functional groups of chitosan have particular interactions with Ag-NPs. Particle size and TEM analyses showed that Chi-Ag-NPs were equivalently dispersed in matrix with an average size of 10-230 nm. The surface morphological structures of chitosan has played important role in influencing the adsorption of Ag-NPs. Chi-Ag-NPs were tested for their bioactive properties and results exhibited higher antioxidant and antibacterial activities by the addition of Ag-NPs. Chi-Ag-NPs composites were non-toxic to L929 fibroblast cells. The present investigation suggested that chitosan will be a good source for the preparation of bionanocomposite materials and also could be useful in different industrial and biomedical applications.

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Section: Diphenyl-1-picryl Hydrazyl Activity (Dpph) Assaymentioning

confidence: 99%

Synthesis and biochemical characterization of silver nanoparticles grafted chitosan (Chi-Ag-NPs): in vitro studies on antioxidant and antibacterial applications

Dara

Mahadevan

Digita³

et al. 2020

SN Appl. Sci.

108

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“…Starch is an abundant biopolymer which comes mainly from grains and tubers and is totally biodegradable [ 1 , 2 , 3 ]. The preparation and utilization of starch nanocrystals (SNCs) originating from starch granules has been extensively studied for many years [ 4 , 5 , 6 , 7 ]. The preparation and physical properties of SNCs have been the subject of great interest and enthusiastic study in recent years [ 8 , 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

An Efficient Approach to Prepare Water-Redispersible Starch Nanocrystals from Waxy Potato Starch

et al. 2021

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Starch nanocrystals (SNCs) are a biodegradable polymer which has been widely studied and used in many fields. In this study, we have developed an efficient procedure for the preparation of SNCs. First, sodium hexametaphosphate (SHMP) and vinyl acetate (VAC) were used to modify waxy potato starch (WPS). Then, the modified starches were hydrolyzed with sulfuric acid to prepare SNCs. Results showed that SNCs prepared with modified starch had higher zeta potentials and better dispersion properties than the original starch. After modification, WPS still maintained its semi-crystalline structure, but the surface became rougher. SHMP-modified WPS showed a decrease in viscosity peak and an increase in gelatinization temperature. VAC-modified WPS showed increased swelling power. Additionally, SNCs prepared with VAC-modified WPS had better water redispersibility and dispersion stability than those from SHMP-modified starch—which will have broader application prospects in the field of safe and biodegradable food packaging.

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“…reported that curcumin release in physiological conditions can be controlled by using sago starch nanoparticles as vehicles. Starch nanoparticles have also been used as carriers of vitamins, like vitamin D 3 and biotin …”

Section: Introductionmentioning

confidence: 99%

“…Starch nanoparticles have also been used as carriers of vitamins, like vitamin D 3 and biotin. [14][15][16] Carotenoids are highly hydrophobic pigments found in plants, algae, and -in some cases -bacteria and fungi. 17 Among carotenoids, the most important is -carotene (BC) due to its relative abundance and pro-vitamin A activity.…”

Section: Introductionmentioning

confidence: 99%

Citric‐acid modified banana starch nanoparticles as a novel vehicle for β‐carotene delivery

2019

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BACKGROUND Starch nanoparticles have become among the most interesting nanovehicles for drug delivery because of their relatively easy synthesis, biocompatibility, and numerous botanical sources. Starch nanoparticles obtained from green bananas were cross‐linked with citric acid and loaded with β‐carotene. RESULTS Mean particle size, encapsulation efficiency, and β‐carotene release in simulated gastric and intestinal fluids and food simulants were studied. Cross‐linked nanoparticles showed higher loading efficiency and encapsulation capacity, indicating that they can accommodate more molecules than their unmodified counterparts, while mathematical models showed a diffusion of released β‐carotene into food simulant media. CONCLUSIONS Cross‐linked nanoparticles showed more controlled release under gastric conditions, mainly in the simulated intestinal fluid, indicating that they are suitable as vehicles for intestine‐specific targeting. This controlled released was also observed in food simulants, with lower release values in the more aqueous simulants. © 2019 Society of Chemical Industry

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Synthesis, characterization and biological evaluation of chitosan film incorporated with β-Carotene loaded starch nanocrystals

Cited by 57 publications

References 27 publications

Synthesis and biochemical characterization of silver nanoparticles grafted chitosan (Chi-Ag-NPs): in vitro studies on antioxidant and antibacterial applications

Synthesis and biochemical characterization of silver nanoparticles grafted chitosan (Chi-Ag-NPs): in vitro studies on antioxidant and antibacterial applications

An Efficient Approach to Prepare Water-Redispersible Starch Nanocrystals from Waxy Potato Starch

Citric‐acid modified banana starch nanoparticles as a novel vehicle for β‐carotene delivery

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