Synthesis, characterization and biological properties of thienyl derived triazole Schiff bases and their oxovanadium(IV) complexes

Chohan, Zahid H.; Sumrra, Sajjad Hussain

doi:10.3109/14756366.2011.582686

Cited by 33 publications

(13 citation statements)

References 33 publications

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“…In addition, all the oxovanadium(IV) complexes (1)-(6) possessed overall significant (55-84%) activity against all the bacterial strains. It is confirmed that antibacterial activity was overall enhanced 31 upon coordination.…”

Section: Antibacterial Bioassay (In Vitro)supporting

confidence: 54%

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In vitro antibacterial, antifungal and cytotoxic activities of some triazole Schiff bases and their oxovanadium(IV) complexes

Sumrra

Chohan

2012

Journal of Enzyme Inhibition and Medicinal Chemistry

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Section: Antibacterial Bioassay (In Vitro)supporting

confidence: 54%

“…[VO(L 31 characteristic amino (NH 2 ) proton at 6.01-6.07 ppm as a singlet which provided an evidence for condensation of only one amino group of triazole moiety. The conclusions drawn from this study provided further support to the modes of bonding discussed earlier in IR spectra.…”

Section: Nomentioning

confidence: 99%

In vitro antibacterial, antifungal and cytotoxic activities of some triazole Schiff bases and their oxovanadium(IV) complexes

Sumrra

Chohan

2012

Journal of Enzyme Inhibition and Medicinal Chemistry

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“…作用机制研究显示, 氯和硝基带有负电, 容易与生物大分子通过氢键发生相互作用, 产生抗微生物作用 [330] . 2 香豆素是一类重要的苯并吡喃酮类结构的杂环化合物, 在医药领域具有广泛的潜在应用 [331] .…”

Section: 吡啶取代的三唑配体含有多个可供配位的氮原子其与 Cu 2＋unclassified

Current Researches and Applications of Azole-BasedSupermolecules as Medicinal Agents

Cheng¹,

Wang²,

Addla³

et al. 2016

Chin. J. Org. Chem.

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Noncovalent bond forces-based supramolecular chemistry grows quite rapidly and has been revealed to have extensively potential applications and huge development values in chemistry, physics, materials and information science, medicine and so on. Azole compounds such as imidazoles, thiazoles, oxazoles, pyrazoles, triazoles, tetrazoles and carbazoles containing special nitrogen aromatic heterocyclic structure, can exert non-covalent forces to form supramolecular complexes with inorganic and/or organic compounds and exhibit broad biological activity. In recent years, heterocyclic azole-based supramolecular complexes have been expeditiously expanding in the field of medicine, and have become a quite hot topic. Combined with our work and referring to other literature in recent 5 years, this paper systematically reviews the researches and applications of azole-based supermolecules as medicinal agents including anticancer, antibacterial, antifungal, antiparasitic, antidiabetic, antihypertensive, anti-inflammatory drugs and other ones. Finally, the perspectives of the future development of azole-based supermolecules as medicinal agents are also presented.

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“…Antifungal activities of all the compounds was studied against six fungal strains (T. longifusus, C. albicans, A. flavus, M. canis, F. solani and C. glabrata) according to literature protocol 22,23 . Sabouraud dextrose agar (Oxoid, Hampshire, England) was seeded with 10 5 (cfu) mL À1 fungal spore suspensions and transferred to petri dishes.…”

Section: In Vitro Antifungal Activitymentioning

confidence: 99%

Metal-based carboxamide-derived compounds endowed with antibacterial and antifungal activity

Hanif

Chohan

Winum

et al. 2013

Journal of Enzyme Inhibition and Medicinal Chemistry

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A series of three bioactive thiourea (carboxamide) derivatives, N-(dipropylcarbamothioyl)-and their cobalt(II), copper(II), nickel(II) and zinc(II) complexes (1)- (12) have been synthesized and characterized by their IR, 1 H-NMR spectroscopy, mass spectrometry and elemental analysis data. The Crystal structure of one of the ligand, N-(dipropylcarbamothioyl)thiophene-2-carboxamide (L 1 ) and its nickel(II) and copper(II) complexes were determined from single crystal X-ray diffraction data. All the ligands and metal(II) complexes have been subjected to in vitro antibacterial and antifungal activity against six bacterial species (Escherichia coli, Shigella flexneri, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus and Bacillus subtilis) and for antifungal activity against six fungal strains (Trichophyton longifusus, Candida albicans, Aspergillus flavus, Microsporum canis, Fusarium solani and Candida glabrata). The in vitro antibacterial and antifungal bioactivity data showed the metal(II) complexes to be more potent than the parent ligands against one or more bacterial and fungal strains.

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Synthesis, characterization and biological properties of thienyl derived triazole Schiff bases and their oxovanadium(IV) complexes

Cited by 33 publications

References 33 publications

In vitro antibacterial, antifungal and cytotoxic activities of some triazole Schiff bases and their oxovanadium(IV) complexes

In vitro antibacterial, antifungal and cytotoxic activities of some triazole Schiff bases and their oxovanadium(IV) complexes

Current Researches and Applications of Azole-BasedSupermolecules as Medicinal Agents

Metal-based carboxamide-derived compounds endowed with antibacterial and antifungal activity

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