Synthesis, characterization and catecholase-like activity of [Mn2L2(μ1,5-dca)2(dca)2]·H2O [L = N,N′-ethylenebis(2-benzoylpyridineimine), dca = dicyanamide]

Abstract

A dinuclear Mn II complex, namely [Mn 2 L 2 -(l 1,5 -dca) 2 (dca) 2 ]ÁH 2 O [L = N,N 0 -ethylenebis(2-benzoylpyridineimine), dca = dicyanamide], has been synthesized and structurally characterized in order to study its catecholaselike activity. Single-crystal X-ray analysis revealed that the molecule possesses a center of inversion at the midpoint of the line bisecting the adjacent metal centers of the dimers. The coordination number of each Mn II center is seven, and the coordination geometry is approximately distorted pentagonal bipyramid. The complex is an efficient catalyst for the oxidation of 3,5-di-tert-butylcatechol to 3,5-di-tert-butylbenzoquinone under air in methanol solution but is inactive in acetonitrile solution. A kinetic study of the catalysis was treated on the basis of the Michaelis-Menten model and reveals high turnover numbers (k cat = 4.5 9 10 2 h -1 ) in methanol.

Synthesis and Characterization of Novel Organocobaloximes as Potential Catecholase and Antimicrobial Activity Agents

“…Catechol oxidase (CO), a type‐III copper protein, catalyzes the oxidation of catechols to the corresponding quinones, a process known as catecholase activity. This helps the higher plants to protect damaged tissues against pathogens and bacteria . Catalytic oxidation of catechols by transition metal complexes has been attracting interest because its relevance to dioxygenase plays a key role in the metabolism of aromatic compounds.…”