Synthesis, characterization and cytocompatibility assessment of hydroxyapatite-polypyrrole composite coating synthesized through pulsed reverse electrochemical deposition

Chakraborty, Rajib; Seesala, Venkata Sundeep; Manna, Jhimli Sarkar; Saha, Partha; Dhara, Santanu

doi:10.1016/j.msec.2018.10.001

Cited by 36 publications

(18 citation statements)

References 39 publications

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“…Sequential electrodepositions of PPy and CaP proposed in the present study appear to be the best method for getting a homogenous and adherent layer of CaP. Similar results were observed with the dual deposition of strontium hydroxyapatite onto PPy films which avoids coating cracking [16,25]. Each PPy coated support was immersed in the electrolyte solution prepared by mixing 25 mM of calcium nitrate tetrahydrate Ca(NO 3 ) 2 .4H 2 O, 15 mM of ammonium phosphate dihydrogen ((NH 4 )H 2 PO 4 ) in permuted water and supplemented with a respectively increasing amount of Na 2 SiO 3 .9H 2 O from 0; 0.3; 0.5; 1 to 2 mM.…”

Section: Calcium Phosphate (Cap) Deposition On Ppy Coated Filmssupporting

confidence: 83%

“…The percentage of live cells was equal to or greater than 75% for all supports, demonstrating their biocompatibility. Comparable osteoblast viability was described on stainless steel supports covered with PPy and hydroxyapatite [25,46]. The addition of 0.5 mM Si enhanced viability as compared to other coatings.…”

Section: Effects Of Multilayer Supports On Pre-osteoblast Behaviormentioning

confidence: 82%

“…Several approaches have recently been developed to improve the biocompatibility and biointegration of PPy by incorporating other materials such as hydroxyapatite nanoparticles or zinc oxide particles [23,24]. Chakraborty et al have also developed a fast method to synthesize hydroxyapatite PPy composites by mixing calcium phosphate (CaP) with Py solution before performing electrodeposition [25]. Another approach to functionalizing PPy coating is the deposition of a second porous layer of strontium hydroxyapatite [16].…”

Section: Introductionmentioning

confidence: 99%

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An efficient and inexpensive method for functionalizing metallic biomaterials used in orthopedic applications

Hamdaoui

Lambert²,

Khireddine³

et al. 2020

Colloid and Interface Science Communications

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Implantations of metallic biomaterials are being carried out more and more frequently due to accident and population aging. Therefore, there is a need for new metallic implants which can combine properties such as durability, biocompatibility and affordability. In this study, multilayer functionalized 316 L stainless steel (SS) supports resistant to steam sterilization were presented. An electropolymerization of pyrrole was performed on SS supports to obtain a protective layer. This polypyrrole coating rendered SS surface resistant to corrosion. Then an electrodeposition of Calcium Phosphate (CaP) doped with increasing concentrations of silicon (Si) ranging from 0 to 2 mM was tested to improve support bone integration. The impacts of silicon addition in the CaP coating without or after steam sterilization were analyzed by profilometry, Scanning Electron Microscopy and Fourier Transform Infrared Spectroscopy. These latter revealed that CaP doped with 0.5 mM of Si constituted the optimal support formulation, presenting sterilization resistance and good biocompatibility.

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Section: Calcium Phosphate (Cap) Deposition On Ppy Coated Filmssupporting

confidence: 83%

Section: Effects Of Multilayer Supports On Pre-osteoblast Behaviormentioning

confidence: 82%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An efficient and inexpensive method for functionalizing metallic biomaterials used in orthopedic applications

Hamdaoui

Lambert²,

Khireddine³

et al. 2020

Colloid and Interface Science Communications

View full text Add to dashboard Cite

show abstract

“…However, this technique requires expensive equipment, maintenance, high temperature, and it is so called the line-of-sight technique. On the contrary, electrochemical deposition is a versatile technique that has been used widely in biomedical applications [ 14 , 15 , 16 ]. Using the electrochemical process to prepare coatings is more cost effective compared to the above mentioned physical deposition methods and the processing temperature is significantly lower.…”

Section: Introductionmentioning

confidence: 99%

Morphological, Chemical, and Biological Investigation of Ionic Substituted, Pulse Current Deposited Calcium Phosphate Coatings

Furkó

Balázsi

2020

Materials

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Ionic substituted calcium phosphate coatings (iCP) have been prepared by the electrochemical pulse current deposition technique with an alternate pulse on and off time of 5 ms onto a titanium alloy substrate. The elemental distribution and morphology of the deposited layers have been extensively studied by scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), and transmission electron microscopy (TEM). The crystallinity and phase structure of iCPs have been investigated by X-ray diffraction (XRD). The corrosion characteristics and biodegradability of coatings have been determined by electrochemical measurements, recording potentiodynamic curves in a physiological solution over a long-term immersion period. The cell viability tests confirmed that the iCP coating was biocompatible, while the corrosion tests proved its biodegradable characteristic. In our paper, we compare the morphological, chemical, and biological characteristics of silver and zinc substituted calcium phosphate layers deposited by the electrochemical method.

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“…Though, most of the works done on polypyrrole include biocompatibility assessment. Thinking about its downsides, including its pitiable dissolvability, additional investigate should be done animal model to affirm the reasonability of polypyrrole as a platform substance [14,15]. The reason for this examination was to explore a conceivable dealing for fixing harmed nerves and to beat the present weaknesses polypyrrole has in tissue building.…”

Section: Introductionmentioning

confidence: 99%

Development of polypyrrole/collagen/nano-strontium substituted bioactive glass composite for boost sciatic nerve rejuvenation in vivo

Lin

Dun

Jin

et al. 2019

Artificial Cells, Nanomedicine, and Biotechnology

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A novel nerve conductor made out of polypyrrole (PPY), collagen (Coll) and nano-strontium substituted bioactive glass (n-Sr@BG) (PPY/Coll/n-Sr@BG) was fabricated by electrospinning. SEM demonstrated that the mean distances across of the pores in the nerve channels were under 15 mm and more prominent than 2 mm. These biocomposite films had biomimetic morphology, bigger porosity and moderately higher surface territory than customary nerve channels, consequently not just allowing the transportation of nerve development factor and glucose yet, in addition, hindering the section of lymphatic tissue and fibroblasts. The consistent filaments of the nerve can copy the characteristic ECM, which is valuable to cell bond, cell multiplication, and cell movement. PPY/Coll/n-Sr@BG demonstrated great cell fondness rate, which is useful for neurilemma cell cells bond, relocation and expansion. Its great viability empowers its wellbeing animal models. Sciatic nerve deformity was crossed over an animal model with PPY/Coll/n-Sr@BG in rodents. PPY/Coll and autotransplants were utilized as control gatherings. Contrasted with PPY/Coll and PPY/Coll/n-Sr@BG accomplished fundamentally increasingly viable recovery of sciatic nerve wounds following 24 weeks implantation and the mean distance across of muscle fibres occasions bigger than that in PPY/Coll/n-Sr@BG, and it was nearer to that in control. The rejuvenated nerve filaments in PPY/Coll/n-Sr@BG had an increasingly standard round shape, the thickness of neuro-filaments in c was more than those in PPY/Coll, and was near that in control. ARTICLE HISTORY

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Synthesis, characterization and cytocompatibility assessment of hydroxyapatite-polypyrrole composite coating synthesized through pulsed reverse electrochemical deposition

Cited by 36 publications

References 39 publications

An efficient and inexpensive method for functionalizing metallic biomaterials used in orthopedic applications

An efficient and inexpensive method for functionalizing metallic biomaterials used in orthopedic applications

Morphological, Chemical, and Biological Investigation of Ionic Substituted, Pulse Current Deposited Calcium Phosphate Coatings

Development of polypyrrole/collagen/nano-strontium substituted bioactive glass composite for boost sciatic nerve rejuvenation in vivo

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