Synthesis, Characterization and Cytotoxicity Evaluation of Nitric Oxide-Iron Oxide magnetic Nanoparticles

Superparamagnetic iron oxide nanoparticles dispersed in Pluronic F127 hydrogel: potential uses in topical applications

“…49 Furthermore, free thiol group (SH) available on the MSA structure can be nitrosated producing NO-releasing nanoparticles, which can then be used as nitric oxide carriers. 9,13,50 As shown in Fig. 2, the spectrum of uncoated Fe 3 O 4 NPs displays only a peak at 580 cm À1 assigned to the (nFe-O).…”

“…Regarding the FTIR spectrum of Fe 3 O 4 -MSA NPs, bands at 580 cm À1 and 3440 cm À1 are assigned to Fe-O (nFe-O) and FeO-H (nFeO-H), respectively. 9,11 The symmetric stretching COO À (n sim. COO À ) can be observed at 1400 cm À1 , while the peak at 1600 cm À1 is attributed to the asymmetric stretching (n assim.…”

“…Superparamagnetic iron oxide nanoparticles, such as Fe 3 O 4 (magnetite), have been employed in a variety of biomedical applications, including diagnostics and drug delivery. [1][2][3][4][5][6][7][8][9][10] Due to the superparamagnetic behavior of Fe 3 O 4 at room temperature, these NPs have a large constant magnetic moment and act as a giant paramagnetic atom, quickly responding to applied magnetic elds without residual magnetism and coercivity. This behavior makes Fe 3 O 4 NPs attractive in a number of biomedical applications.…”

Biocompatible superparamagnetic nanoparticles with ibuprofen as potential drug carriers

“…Particularly, surface coating of NPs with biocompatible molecules based on a core-shell system is an interesting approach to avoid aggregation in aqueous media [19]. There are several molecules suitable to functionalize SPIONs surfaces [17, [20][21][22] such as thiol groups from mercaptosuccinic acid (MSA), dimercaptosuccinic acid (DMSA) [10,23,24] glutathione (GSH), cysteine (Cys) [24][25][26], and silica [27,28]. Vinluan et al [22] has shown that the surface modification with Glutathione (GT), an endogenous antioxidant composed of glutamic acid, cysteine and glycine, increases the physiological stability and agglomeration resistance of the NPs to certain proteins.…”