Synthesis, Characterization and Hypoglycemic Activity of Cr (III) Complexes of Sulphonyl-ureas, As Oral Antidiabetics

Abstract

Synthesis, characterization and hypoglycemic activity of chromium(III) complexes with Gliclazide (GLC), Glibenclamide (GLB) and Glimeperide (GLM) oral antidiabetic allopathic drugs have been studied. The conductometric titration using monovariation method indicates that complexes are non-ionic and L 2 M type. Analytical data agrees with the molecular formulae of complexes viz.