Synthesis, characterization and <i>in vitro</i> evaluation of cytotoxicity and antimicrobial activity of chitosan–metal nanocomposites

Kaur, Pawan; Thakur, Rajesh; Barnela, Manju; Chopra, Meenu; Manuja, Anju; Chaudhury, Ashok

doi:10.1002/jctb.4383

Cited by 53 publications

(21 citation statements)

References 17 publications

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“…For each treatment, three replicates were maintained. The antifungal efficiency of AgNPs in terms of percentage inhibition of mycelium growth was calculated using the formula:

% inhibition = \frac{Mc - Mt}{italicMc} \times 100

where Mc is mycelium growth in the control, Mt is mycelium growth in the treatment…”

Section: Methodsmentioning

confidence: 99%

“…Use of nanoparticles as antimicrobial agents is a very advanced strategy with several benefits compared with conventional approaches . In our laboratory, antibacterial and antifungal activities of various nanoparticles against human and plant pathogens were evaluated . Among the nanoparticles, silver nanoparticles are among the most efficient antimicrobials and are a subject of interest for researchers and scientists .…”

Section: Introductionmentioning

confidence: 99%

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Management of wilt disease of chickpea in vivo by silver nanoparticles biosynthesized by rhizospheric microflora of chickpea (Cicer arietinum)

Kaur

Thakur

Duhan

et al. 2018

J of Chemical Tech & Biotech

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BACKGROUND This work reports the isolation and screening of rhizospheric microflora of chickpea and their role in the biosynthesis of silver nanoparticles (AgNPs). The antifungal potential of AgNPs for control of wilt disease of chickpea, caused by Fusarium oxysporum f. sp. ciceri (FOC) was evaluated in vitro and in vivo pot experiments. The effect of AgNPs on seed germination and soil community was also evaluated. RESULTS Among microbial strains, two bacteria, Pseudomonas sp. and Achromobacter sp. and two fungi, Trichoderma sp. and Cephalosporium sp., were identified for biosynthesis of AgNPs. AgNPs were confirmed by UV‐visible spectra (λ = 420 nm) and transmission electron microscopy (TEM) with size 20–50 nm. AgNPs showed very high antifungal activity (95%) against FOC in vitro at 100 µgmL−1 concentration. Pot experiments showed maximum and minimum reduction in wilt incidence over control, i.e. 73.33% for AgNPs and copper‐oxychloride (CuOCl) i.e. 26.67%, respectively. Seeds coated with AgNPs showed high germinability up to 98% and no negative impact was observed on soil community. CONCLUSION This study demonstrated the role of AgNPs against the fungal disease of chickpea that can be extended to other diseases of chickpea and other important Indian crops. © 2018 Society of Chemical Industry

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“…For each treatment, three replicates were maintained. The antifungal efficiency of AgNPs in terms of percentage inhibition of mycelium growth was calculated using the formula:

% inhibition = \frac{Mc - Mt}{italicMc} \times 100

where Mc is mycelium growth in the control, Mt is mycelium growth in the treatment…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Management of wilt disease of chickpea in vivo by silver nanoparticles biosynthesized by rhizospheric microflora of chickpea (Cicer arietinum)

Kaur

Thakur

Duhan

et al. 2018

J of Chemical Tech & Biotech

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“…Moreover, the antimicrobial properties of chitosan were improved by charging chitosan with different metals (Kaur et al . ). Chitosan‐silver nanocomposites fabricated by embedding of silver nanoparticles in chitosan polymer and its antimicrobial activity was evaluated against Staph.…”

Section: Role Of Various Nanomaterials For the Management Of Infectionsmentioning

confidence: 97%

“…Ahmad et al (2012) explored silver bionanocomposites (Ag BNCs) for its antibacterial activity against Gram-negative and Gram-positive bacteria. Moreover, the antimicrobial properties of chitosan were improved by charging chitosan with different metals (Kaur et al 2015). Chitosan-silver nanocomposites fabricated by embedding of silver nanoparticles in chitosan polymer and its antimicrobial activity was evaluated against Staph.…”

Section: Nanocompositesmentioning

confidence: 99%

Nanotechnology based anti-infectives to fight microbial intrusions

et al. 2016

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SummaryWith the rise in human population across the globe especially in developing countries, the incidence of microbial infections are increasing with greater pace. On the other hand, available medication and therapies are found to be insufficient for the complete cure of such microbial infections due to the development of resistance against various antibiotics. Therefore, to cope up the menace of microbial infections and drug resistance, there is demand for new and compelling technology, which has the ability to impede these problems. Many research groups worldwide are finding a ray of hope in nanomaterials owing to their unique properties. In the present review we have discussed the reasons behind the development of new materials based on nanotechnology. It is mainly focused on pioneering studies on application of nanomaterials like carbon nanotube, fullerene, dendrimers, nanocomposite and metal nanoparticles in combating dreadful pathogens. Moreover, the concerns about their toxicity have also been discussed.

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“…Another approach to improve the effectiveness of antimicrobial protection is the tailoring of different antimicrobial coatings to obtain complex with dual activity (e.g. applying silver chloride and Si-QAC composite) [36,[56][57][58][59][60][61].…”

Section: Study In Hospital Environmentmentioning

confidence: 99%

Efficiency of Medical Workers’ Uniforms with Antimicrobial Activity

Rozman¹,

Pavlinić²,

Pal³

et al. 2017

Textiles for Advanced Applications

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Antimicrobial finishing of textiles protects users from pathogenic microorganisms, which can cause medical and hygienic problem. The use of such textiles particularly increases in healthcare facilities, where reduction and transmission of pathogenic bacteria are important factors for preventing nosocomial infections. In the present study, the efficiency of fabric with silane quaternary ammonium compounds (Si-QAC) applied as active agents was evaluated. A test was performed according to ATCC 100-1999 Test Method after 0-, 24-and 48-hour incubation times. The treated textiles were effective against Enterococcus faecalis, Staphylococcus aureus and Klebsiella pneumoniae, but were not effective for Gramnegative Escherichia coli and Pseudomonas aeruginosa. Testing was also performed in hospital environment at infectious department where working clothes made of treated fabric were compared to normal working clothes. Antimicrobial textiles were not effective in a hospital environment, where average microbial count on medical workers' uniforms without antimicrobial protection was 1.4 × 10 9 cfu/mL, and 1.3 × 10 9 cfu/mL for uniforms made of antimicrobial material. Our conclusion is that quantities of application rates for Si-QAC should be higher or should be improved with applying another antimicrobial coating to obtain complex with dual activity.

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Synthesis, characterization and in vitro evaluation of cytotoxicity and antimicrobial activity of chitosan–metal nanocomposites

Cited by 53 publications

References 17 publications

Management of wilt disease of chickpea in vivo by silver nanoparticles biosynthesized by rhizospheric microflora of chickpea (Cicer arietinum)

Management of wilt disease of chickpea in vivo by silver nanoparticles biosynthesized by rhizospheric microflora of chickpea (Cicer arietinum)

Nanotechnology based anti-infectives to fight microbial intrusions

Efficiency of Medical Workers’ Uniforms with Antimicrobial Activity

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