“…Therefore, high-efficiency methods or active synthesized compounds are required for eliminating or decreasing these problems. Over recent years, enhancing new and easy processes for the generation of essential heterocyclic compounds have been dealt with ( Yavari et al, 2007 ; Yavari et al, 2008 ; Yavari et al, 2009 ; Yavari et al, 2010 ; Hajinasiri et al, 2011 ; Rostami Charati et al, 2011 ; Rustaiyan, and Ezzatzadeh, 2011 ; Ezzatzadeh et al, 2012 ; Tavakolinia et al, 2012 ; Hossaini et al, 2014 ; Rajabi et al, 2015 ; Rostami-Charati et al, 2015 ; Rezayati et al, 2016 ; Sajjadi-Ghotbabadi et al, 2016 ; Rostami-charati et al, 2017a ; Rostami-Charati et al, 2017b ; Hossaini et al, 2017 ; Ezzatzadeh 2018 ; Rezayati et al, 2018 ; Ezzatzadeh and Hossaini, 2019a ; Ezzatzadeh and Hossaini 2019b ; Seifi Mansour et al, 2019 ; Ezzatzadeh and Hossaini 2020a ; Aghahosseini, and Ramazani, 2020 ; Ahmadi et al, 2020 ; Baghernejad and Fiuzat 2020 ; Ezzatzadeh and Hossaini, 2020b ; Ebrahimi et al, 2020 ; Ghanaat et al, 2020 ; Haddazadeh and Mohammadi, 2020 ; Hakimi et al, 2020 ; Khazaei et al, 2020 ; Mostaghni and Taat, 2020 ; Nikpassand and Zare Fekri, 2020 ; Raoufi et al, 2020 ; Rohaniyan et al, 2020 ; Sajjadifar et al, 2020 ; Taran et al, 2020 ; Tayebee and Gohari, 2020 ; Baghernejad and Nazari, 2021 ; Baghernejad and Rostami Harzevili, 2021 ; Kamali and Shirini, 2021 ; Karimi et al, 2021 ; Mohammed Abd Al-Mohson 2021 ; Salih and Al-Messri, 2021 ). In this research, initially, a green procedure was employed for the generation of new spiro-1,2,4-triazine 7 via MCRs of activated carbonyl compound 1 , acetophenones 2 , diethyl oxalate 3 , ammonium acetate 4 , malononitrile 5 , and hydrazoyl chloride 6 in the aqueous form at room temperature in the vicinity of Ag/Fe 3 O 4 /CdO@MWCNT MNCs as an ...…”