Synthesis, characterization, biological activity and molecular docking studies of novel schiff bases derived from thiosemicarbazide: Biochemical and computational approach

Synthesis, spectral and thermal studies of new Schiff base copper(II) complexes with their biological effect on Entomopathogenic nematodes

“…The 1 H NMR spectrum of the ligand H2L 2 displayed singlet at δ 11.28 ppm and at δ 13.50 ppm corresponding to the o-phenolic-OH and the p-phenolic-OH protons, respectively. [18,28] Additionally, the 1 H NMR spectrum of the ligand H2L 2 exhibits multiplets at δ 8.54-6.80 ppm assigned to aromatic protons. The 1 H NMR spectra of ligands L 1 and H2L 2 showed signals of pyrrole moiety appeared at δ 6.344 ppm (m, 1H, =CH-).…”

“…[9][10][11] Schiff bases have been vastly elaborated because they have several motivating features such as photochromic and thermochromic properties, [12] proton shift tautomeric equilibria, [13] biological and pharmacological activities [14][15][16][17] in addition to analytical application. [18,19] Because Schiff bases form steady complexes with the majority of transition, nontransition, lanthanides and actinide metals, they have played an essential role in the development of coordination chemistry. [20,21] Schiff bases are excellent candidates for synthesizing metal complexes that are useful in bioinorganic chemistry, catalysis encapsulation, transport and separation methods and magneto-chemistry.…”

Discovery of Novel 3,4-Dihydro-2(1H)-Quinolinone Sulfonamide Derivatives as New Tubulin Polymerization Inhibitors with Anti-Cancer Activity

“…Both 3,4-dihydroquinolin-2(1 H )-one and sulfonic chloride were chlorosulfonated to obtain intermediate A . Moreover, 3,4,5-trimethoxyaniline and different substituted aldehydes were subjected to the Schiff’s base reaction to obtain different intermediates B [ 21 , 22 , 23 ]. Subsequently, intermediate B was reduced to obtain C .…”

Synthesis, Characterization, Investigation of AChE Activities and Molecular Docking Studies of New Schiff Bases Based on Substitute Salicyl Aldehyde

“…Schiff bases has various applications including paint, catalyst and organic intermediates etc. Moreover, Schiff bases have shown to exhibit various biological activities anti-diabetic, antibacterial, Alzheimer's, antimalarial, antifungal, anti-inflammatory, antipyretic, antiviral and antiproliferative [1][2][3][4][5][6][7]. Imine groups (-CH=N-) are found in the structure of many natural compounds and the effect of this group is very important for biological activities [8].Therefore, the number of publications on Schiff bases in the fields of chemistry, pharmacy, biochemistry and industry is quite high and continues to increase [9].…”