Synthesis, characterization, crystal structures and biological activities of eight-coordinate zirconium(IV) Schiff base complexes

Sahraei, Atefeh; Kargar, Hadi; Hakimi, Mohammad; Tahir, Muhammad Nawaz

doi:10.1007/s11243-017-0152-x

Cited by 68 publications

(5 citation statements)

References 24 publications

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“…The antifungal activity of synthesized dihydropyrimidine derivatives 1 and 2 was studied against Candida albicans and Aspergillus niger fungi by determining minimal inhibitory concentrations (MIC) by the twofold micro-dilution method as described in [47][48][49][50][51][52][53]. The compounds were prepared according to CLSI guidelines and diluted in U-bottom 96 well microtiter plates which contained Sabouraud liquid medium.…”

Section: Biological Assaymentioning

confidence: 99%

Crystal structure, Hirshfeld surface analysis, computational and antifungal studies of dihydropyrimidines on the basis of salicylaldehyde derivatives

et al. 2022

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HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

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Section: Biological Assaymentioning

confidence: 99%

Crystal structure, Hirshfeld surface analysis, computational and antifungal studies of dihydropyrimidines on the basis of salicylaldehyde derivatives

et al. 2022

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“…Many researchers have been synthesized metal complexes with Schiff base ligands and tested for antibacterial activity (13)(14)(15)(16) . The significant antibacterial activity displayed by these metal complexes.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Evaluation of Antifungal Activity of Synthesized Novel Zn(II) Complex with Schiff base Ligand

Meena,

Serawat,

Gunsaria

2023

IJST

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Objectives:The current study is concerned with creating a Zn(II) complex with a novel schiff base ligand and to evaluate the Zn(II) metal complex's in-vitro antifungal efficacy against Candida albicans, Candida glabrata, Candida krusei, and Candida tropicali. Methods: N, N'-bis(2-hydroxy-3methoxybenzaldehyde)-2-phenyl-1,3-propanediamine was synthesized by using 2-hydroxy-3-methoxybenzaldehyde and 2-phenyl-1,3-propanediamine. Metal precursor Zn(OAc) 2 .2H 2 O react with the ligand to form Zn(II) metal complex. The structure of the synthesis complex was confirmed by elemental analysis i.e. 1H-NMR, IR and MS spectroscopy. Findings : Zn(II) schiff base complexes have unique characteristics and unusual reactivity, which operate as a foundation for the development of complex molecules with potential use in a wide range of applications. One of the most typical fungal infections is candidiasis. The findings suggest that the Zn(II) metal complex could be a promising antifungal agent. Novelty: Characterization and unique properties of the newly synthesized zinc complex and its potential as a novel class of antifungal agent.

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“…Some SBs derivatives have demonstrated α-glucosidase inhibition and antiglycation activity [ 19 , 20 ], whereas other derivatives were synthesized and used as fluorescent sensors for the diabetic biomarker beta-hydroxybutyrate (β-HB) [ 21 ]. Metal complexes of different metals with SBs have demonstrated a myriad of activities [ 22 , 23 ], and catalytic applications [ 24 ] in which metals are represented by Mo [ 25 ], Cu [ 26 , 27 , 28 ], Zr [ 29 , 30 , 31 ], Pd [ 32 ], Cu [ 33 ], Ni [ 34 ], Ru [ 35 ], Mn [ 36 ], Zn [ 37 , 38 ] and W [ 39 ]. Several studies have been carried out on the transmetalation of Zn-SB complexes with other metal ions [ 40 ] for various purposes, such as the detection of Cu 2+ ions in aqueous solution [ 41 ] and the inhibition of acid-induced steel corrosion [ 42 ].…”

Section: Introductionmentioning

confidence: 99%

Metal Complexes with Schiff Bases: Data Collection and Recent Studies on Biological Activities

Sinicropi

Ceramella

Iacopetta

et al. 2022

IJMS

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Metal complexes play a crucial role in pharmaceutical sciences owing to their wide and significant activities. Schiff bases (SBs) are multifaceted pharmacophores capable of forming chelating complexes with various metals in different oxidation states. Complexes with SBs are extensively studied for their numerous advantages, including low cost and simple synthetic strategies. They have been reported to possess a variety of biological activities, including antimicrobial, anticancer, antioxidant, antimalarial, analgesic, antiviral, antipyretic, and antidiabetic ones. This review summarizes the most recent studies on the antimicrobial and antiproliferative activities of SBs-metal complexes. Moreover, recent studies regarding mononuclear and binuclear complexes with SBs are described, including antioxidant, antidiabetic, antimalarial, antileishmanial, anti-Alzheimer, and catecholase activities.

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Synthesis, characterization, crystal structures and biological activities of eight-coordinate zirconium(IV) Schiff base complexes

Cited by 68 publications

References 24 publications

Crystal structure, Hirshfeld surface analysis, computational and antifungal studies of dihydropyrimidines on the basis of salicylaldehyde derivatives

Crystal structure, Hirshfeld surface analysis, computational and antifungal studies of dihydropyrimidines on the basis of salicylaldehyde derivatives

In Vitro Evaluation of Antifungal Activity of Synthesized Novel Zn(II) Complex with Schiff base Ligand

Metal Complexes with Schiff Bases: Data Collection and Recent Studies on Biological Activities

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