Synthesis, chemosensing properties and logic behaviour of a novel ratiometric 1,8-naphthalimide probe based on ICT and PET

Georgiev, Nikolai I.; Dimitrova, M.; Todorova, Yoana D.; Bojinov, Vladimir B.

doi:10.1016/j.dyepig.2016.03.051

Cited by 62 publications

(14 citation statements)

References 76 publications

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“…[15][16][17][18] Several 1,8-naphthalimide chemosensors have been developed for detection of cations, anions, and small polar molecules. [19][20][21][22] However, 1,8-naphthalimide based chemosensors with selective response to Ba 2+ remain underdeveloped. 9,23 Selective barium sensing has been demonstrated by a relatively small number of instructive fluorescent chemosensors.…”

Section: Introductionmentioning

confidence: 99%

Demonstration of Selective Single-Barium Ion Detection with Dry Diazacrown Ether Naphthalimide Turn-on Chemosensors

et al. 2021

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Single molecule fluorescence detection of barium is investigated for enhancing the sensitivity and robustness of a neutrinoless double beta decay (0νββ) search in 136 Xe, the discovery of which would alter our understanding of the nature of neutrinos and the early history of the Universe. A key developmental step is the synthesis of bariumselective chemosensors capable of incorporation into ongoing experiments in high-pressure 136 Xe gas. Here we report turn-on fluorescent naphthalimide chemosensors containing monoaza-and diaza-crown ethers as agents for single Ba 2+ detection. Monoaza-18-crown-6 ether naphthalimide sensors showed sensitivity primarily to Ba 2+ and Hg 2+ , whereas two diaza-18-crown-6 ether naphthalimides revealed a desirable selectivity toward Ba 2+ . Solution-phase fluorescence and NMR experiments support a photoinduced electron transfer mechanism enabling turn-on fluorescence sensing in the presence of barium ions. Changes in ion-receptor interactions enable effective selectivity between competitive barium, mercury, and potassium ions, with detailed calculations correctly predicting fluorescence responses. With these molecules, dry-phase single Ba 2+ ion imaging with turnon fluorescence is realized using oil-free microscopy techniques. This represents a significant advance toward a practical method of single Ba 2+ detection within large volumes of 136 Xe, plausibly enabling a background-free technique to search for the hypothetical process of 0νββ.

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Section: Introductionmentioning

confidence: 99%

Demonstration of Selective Single-Barium Ion Detection with Dry Diazacrown Ether Naphthalimide Turn-on Chemosensors

et al. 2021

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“…Thus, excited electron transfers from ICT state to the ground state, which produces a change in D–A molecule emission . Based on the charge transfer, PET and ITC are common mechanisms for designing fluorescence switches . By using PET and ICT fluorescent probes 1,8‐naphthalimide as energy donor, a series FRET systems were realized .…”

Section: Resultsmentioning

confidence: 99%

Fluorescent Platforms Based on Organic Molecules for Chemical and Biological Detection

Wang

Liu

Zhu

et al. 2018

Physica Rapid Research Ltrs

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Fluorescent platforms based on organic molecules have attracted great attention in the field of chemical and biological detection because of their high detection efficiency and sensitivity. Strategies in fluorescent platform design with controlled luminescence properties based on Förster resonance energy transfer, excimer/exciplex formation, and metal‐enhanced fluorescence mechanisms are reviewed herein. Attention is focused on the photophysical processes of fluorescent molecules in their interactions with other components as well as with the target. Color‐ and intensity‐tunable luminescence from energy or electron transfer and the electronic structures of fluorescent molecules are discussed. On the basis of the photophysical properties of fluorescent molecules, their responsive fluorescence signals, which reflect specific inter‐ and intra‐molecular interactions, are particularly effective for chemical and biological detection.

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“…Then samples were incubated at 37 °C for three hours using shaker incubator. In the next step, samples were based probes, ion sensors, cellular imaging, and DNA targeting [57][58][59][60][61][62]. In addition, recent reports have been shown that polycarbonate based urethanes have great blood compatibility [34][35][36][37].…”

Section: Biocompatibility Testsmentioning

confidence: 99%

Evaluation of the Mechanical Properties and Blood Compatibility of Polycarbonate Urethane and Fluorescent Self-Colored Polycarbonate Urethane as Polymeric Biomaterials

Zamani¹,

Yahyaei²

2020

Preprint

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<p>Fluorescent polymeric biomaterials have got significant attention due to their promising applications in biomedical fields such as labeling, monitoring, diagnostics, imaging and tracking. Polycarbonate urethane (PCU) and 1,8-naphthalimide based fluorescent dyes separately have been studied and shown great biocompatibility and physical properties. Therefore, in this work we have taken advantage of excellent fluorescence properties of naphthalimide dye and biocompatibility of PCU, and covalently attached the fluorescent dye to the PCU (self-colored PCU). Covalent attachment can increase the stability of the dye in the biomedical applications especially when biomaterials are in contact with blood and can inhibit the release of the dye to surrounding media. DMTA, AFM, and contact angle measurement were used to study the mechanical and morphological properties of the self-colored PCU and results showed that incorporation of the dye to the PCU did not change the mechanical and morphological properties of the PCU. In addition, MTT assay, hemolysis assay, PT and aPTT assays as well as protein adsorption assay was used to evaluate the blood compatibility of PCU and self-colored PCU and results indicated great bio and blood compatibility of these materials. These great mechanical and blood compatibility properties of the self-colored PCU as well as their excellent fluorescent properties suggested that, these materials could be an ideal candidates to be use in biomedical applications in which non-invasive and non-destructive fluorescent based techniques are required. </p>

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Synthesis, chemosensing properties and logic behaviour of a novel ratiometric 1,8-naphthalimide probe based on ICT and PET

Cited by 62 publications

References 76 publications

Demonstration of Selective Single-Barium Ion Detection with Dry Diazacrown Ether Naphthalimide Turn-on Chemosensors

Demonstration of Selective Single-Barium Ion Detection with Dry Diazacrown Ether Naphthalimide Turn-on Chemosensors

Fluorescent Platforms Based on Organic Molecules for Chemical and Biological Detection

Evaluation of the Mechanical Properties and Blood Compatibility of Polycarbonate Urethane and Fluorescent Self-Colored Polycarbonate Urethane as Polymeric Biomaterials

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