Synthesis, computational and optical studies of tetraphenylethene-linked Pd(<scp>ii</scp>)dipyrrinato complexes

Gupta, Iti; Manav, Neha; Singh, Rajvir; Janaagal, Anu; Yadav, Amit Kumar Singh; Pandey, Vijayalakshmi

doi:10.1039/d2nj02719d

Cited by 10 publications

(2 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The study of singlet oxygen production by RP1 and RP2 was conducted in water using Rose Bengal as the standard. 52,53 A reduction in the intensity of DPBF at 420 nm was observed on a UV-vis spectrometer, as shown in the plots of absorbance versus time in Fig. 9 and S6 †.…”

Section: Resultsmentioning

confidence: 82%

Imaging of mitochondria/lysosomes in live cells and C. elegans

et al. 2023

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 82%

Imaging of mitochondria/lysosomes in live cells and C. elegans

et al. 2023

View full text Add to dashboard Cite

show abstract

“…The deviation between the calculated and observed λ max was observed due to limitations of vertical approximations. [31] Interestingly, the LUMOs of com-…”

Section: Dft and Td-dft Studiesmentioning

confidence: 99%

Dibenzothiophene Bridged Bis‐Bodipy and Bis‐Metal Dipyrrin Complexes

Kaur,

Ravikanth

2024

ChemistrySelect

View full text Add to dashboard Cite

Dibenzothiophene (DBT) bridged bis‐dipyrromethane was synthesized by treating readily available 4,6‐di(p‐formylphenyl) dibenzothophene with pyrrole under acid catalyzed conditions. The DBT bridged bis‐dipyrromethane was further oxidized with DDQ to afford the DBT bridged bis‐dipyrrin which was used as a ligand to prepare DBT bridged bis‐BODIPY, bis‐Ni(II) dipyrrin and bis‐Pd(II) dipyrrin complexes by treating the ligand with BF3 ⋅ Et2O, Ni(acac)2 and Pd(acac)2 respectively under mild reaction conditions. The DBT‐bridged bis‐BODIPY and bis‐metal dipyrrin complexes were thoroughly characterized and studied by HR‐MS, 1D & 2D NMR, absorption, fluorescence, cyclic voltammetry and DFT techniques. The bis‐BODIPY and bis‐Pd(II) dipyrrin showed highly intense absorption band at ~500 nm along with one low intense absorption band at 340 nm whereas the bis‐Ni(II) dipyrrin complex showed slightly broadened blue shifted high intense band at 490 nm along with one additional band at 426 nm. The bis‐BODIPY was fluorescent with fluorescence band at 524 nm and quantum yield of 0.031 whereas bis‐M(II) dipyrrin complexes were nonfluorescent. DFT optimized structures revealed that the BODIPY units are more planar with the dibenzophene moiety in bis‐BODIPY with an angle of ∼5.68°. However, in 3‐Pd and 3‐Ni, the M(II)‐dipyrrin units are much more deviated from the dibenzothiophene plane with an angle of 12.81°–14.23°.

show abstract

Synthesis and Spectroscopic Study of a Homogenous Bimetallic Os(II) Complex as a New Gastric Cancer Photosensitizer

Lu,

Chen

2024

Chemistry A European J

View full text Add to dashboard Cite

A homogenous dinuclear Os(II) complex bisOs was synthesized and fully characterized. The electrochemical cyclic voltammetry study, and density functional theory (DFT) and time‐dependent DFT (TD‐DFT) calculations were performed to investigate the electronic property. bisOs showed an obvious interaction with lipase and BSA, and can generate singlet oxygen under blue and red LED light irradiation, with a singlet oxygen quantum yield (ΦΔ) of 0.36 in comparison to that of [Ru(bpy)3]Cl2 in acetonitrile. bisOs exhibited moderate to great photocytotoxicity against HGC‐27 human gastric cancer cells under blue LED light irradiation, giving the IC50 value as low as 1.83 μM (PI value is 9.7), while was almost non‐cytotoxic in the dark. The cellular singlet oxygen detection in HGC‐27 cancer cells exhibited a concentration‐dependent manner, and cell uptake of bisOs in A549 cells was as high as 120 ng/106 cells, subcellular colocalization study indicated that bisOs was not accumulated in nucleus, and less likely to target mitochondria. This work provides a new example of dinuclear osmium complex as potential photosensitizer candidate for gastric treatment.

show abstract

Synthesis, computational and optical studies of tetraphenylethene-linked Pd(ii)dipyrrinato complexes

Abstract: This work is focused on the design and synthesis of homoleptic & heteroleptic dipyrrinato complexes with palladium at the centre. The C-5 position of dipyrrin ligand was substituted with pentaflourophenyl/naphthalene/tetraphenylethylene...

Cited by 10 publications

References 54 publications

Imaging of mitochondria/lysosomes in live cells and C. elegans

Imaging of mitochondria/lysosomes in live cells and C. elegans

Dibenzothiophene Bridged Bis‐Bodipy and Bis‐Metal Dipyrrin Complexes

Synthesis and Spectroscopic Study of a Homogenous Bimetallic Os(II) Complex as a New Gastric Cancer Photosensitizer

Contact Info

Product

Resources

About