Synthesis, Crystal Structure, and Insecticidal Activity of Novel N-Alkyloxyoxalyl Derivatives of 2-Arylpyrrole

Abstract

Two series of novel N-alkyloxyoxalyl derivatives of 2-arylpyrrole were synthesized, and their structures were characterized by (1)H NMR spectroscopy, elemental analysis, and single-crystal X-ray diffraction analysis. The insecticidal activities of the new compounds were evaluated. The results of bioassays indicated that some of these title compounds exhibited excellent insecticidal activities, and their insecticidal activities against oriental armyworm, mosquito, and spider mite are comparable to those of the commercialized Chlorfenapyr.

Copper‐Catalyzed C(sp3)−H/C(sp3)−H Cross‐Dehydrogenative Coupling with Internal Oxidants: Synthesis of 2‐Trifluoromethyl‐Substituted Dihydropyrrol‐2‐ols

“…Zuschriften various significant, privileged, and attractive trifluoromethylated heterocycles with relevance for medicinal chemistry, such as trifluoromethylated furan 5a, [11] thiophene 6a, [12] pyrroles 7a and 8a, [13] dihydropyridazine 9a, [14] and pyridazine 10 a. [15] Pyrrole 8ais atrifluoromethylated analogue of an Ab 42 lowering agent, and could be ac ompetitive potential drug candidate.…”

“…Furthermore, different inorganic and organic bases were used as additives (entries [13][14][15][16][17][18][19][20]. Other metal catalysts such as Pd(OAc) 2 ,Rh 2 (OAc) 4 ,orFeCl 3 did not show any catalytic activity,and the desired product was not detected in the absence of copper catalyst (entry 12).…”

Synthesis, Characterization, and Antifungal Activity of Phenylpyrrole-Substituted Tetramic Acids Bearing Carbonates

“…As with many other five-membered heterocyclic compounds, pyrrole derivatives are highly significant in agrichemistry, many of these compounds have been widely used, given their fungicidal [16,17], insecticidal [18,19], and herbicidal [20] activities. In this work, we would like to introduce pyrrole to the 3-position of pyrrolidine-2,4-dione to design and synthesize 17 novel tetramic acid derivatives for revealing the influence of introduced groups (substituted phenylpyrroles and carbonates) on fungicidal activity of pyrrolidine-2,4-diones.…”

Diverse outcomes of CO2 fixation using alkali metal amides including formation of a heterobimetallic lithium–sodium carbamato-anhydride via lithium–sodium bis-hexamethyldisilazide

“…16 Another class of compound that has received much synthetic interest are pyrroles. This is due to the prevalence of the five-membered ring in areas ranging from agricultural chemistry 17 to the pharmaceutical industry. 18 Herein we report the different outcomes of the insertion reactions of CO 2 into common utility lithium amides, namely LDA and lithium pyrrolide.…”