Synthesis, crystal structure, experimental and theoretical studies of tetradentate N2O2 Schiff base ligand and its Ni(II) and Pd(II) complexes

Kargar, Hadi; Torabi, Vajiheh; Akbari, Alireza; Behjatmanesh–Ardakani, Reza; Tahir, Muhammad Nawaz

doi:10.1007/s13738-018-01583-1

Cited by 23 publications

(1 citation statement)

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“…The azomethine-containing species produce a superior class of ligands that are unrivalled in their variety, similarity to naturally occurring biological molecules, and relevance to metabolic processes occurring in biological systems (2) . So many researchers (3)(4)(5)(6) collectively emphasize the paramount importance and versatile applications of N2O2 Schiff base ligands and their corresponding metal complexes in the fields of coordination chemistry and theoretical studies. These ligands serve as essential building blocks for constructing diverse transition metal complexes, enabling precise control over coordination geometries and electronic properties, which in turn, https://www.indjst.org/ holds significant implications for catalysis, materials science, and the development of functional materials.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Evaluation of Antifungal Activity of Synthesized Novel Zn(II) Complex with Schiff base Ligand

Meena,

Serawat,

Gunsaria

2023

IJST

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Objectives:The current study is concerned with creating a Zn(II) complex with a novel schiff base ligand and to evaluate the Zn(II) metal complex's in-vitro antifungal efficacy against Candida albicans, Candida glabrata, Candida krusei, and Candida tropicali. Methods: N, N'-bis(2-hydroxy-3methoxybenzaldehyde)-2-phenyl-1,3-propanediamine was synthesized by using 2-hydroxy-3-methoxybenzaldehyde and 2-phenyl-1,3-propanediamine. Metal precursor Zn(OAc) 2 .2H 2 O react with the ligand to form Zn(II) metal complex. The structure of the synthesis complex was confirmed by elemental analysis i.e. 1H-NMR, IR and MS spectroscopy. Findings : Zn(II) schiff base complexes have unique characteristics and unusual reactivity, which operate as a foundation for the development of complex molecules with potential use in a wide range of applications. One of the most typical fungal infections is candidiasis. The findings suggest that the Zn(II) metal complex could be a promising antifungal agent. Novelty: Characterization and unique properties of the newly synthesized zinc complex and its potential as a novel class of antifungal agent.

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