Synthesis, crystal structures and IR spectra of isotypic pseudopolymorphs complexes of Zn(II) by indole-2-carboxylic acid and 2,9-dimethyl-1,10-phenanthroline with different solvates (DMA, DMF or DMSO)
“…The Co–O bond distances of 2.117(8), 2.128(6), 2.220(10) and 2.220(10) Å are similar to reported values [39–47]. Co–N bond distances of 2.090(7) and 2.100(7) Å are also similar to reported values [39–48]. Selected angles and distances are listed in Table 1.Fig.…”
Four novel complexes [Co(H2O)4(sul)2] 1, [Co(2-ampy)2(sul)2] 2, [Co(H2O)2(1,10-phen) (sul)2] 3 and [Co(2,9-dimephen)(sul)2] 4 (sul = sulindac, 2-ampy = 2-amino pyridine, 1,10-phen = 1,10-phenanthroline and 2,9-dimeph = 2,9-dimethyl-1,10-phenanthroline) were prepared and characterized by IR, UV–Visible spectroscopy and magnetic properties. The crystal structures of complexes 1 and 4 were determined by single-crystal X-ray diffraction. In-vitro anti-bacterial activity for the prepared complexes against Gram-positive (Staphylococcus epidermidis, Staphylococcus aureus) and Gram-negative (Bordetella, Escherichia coli) bacteria and Yeast species (Saccharomyces and Candida) were performed using agar well-diffusion method. Only complex 4 showed reasonable activity against yeast. All compounds showed more anti-bacterial activity against Gram-positive bacteria than Gram-negative.Graphical abstractThis work reports synthesis, crystallographic, spectroscopic studies and biological activity of new cobalt(II) complexes with bioactive mixed sulindac and nitrogen-donor ligands. The crystal structures of complexes 1 and 4 were determined using single-crystal X-ray diffraction.
In-vitro anti-bacterial activity of the prepared complexes and their parent ligands were investigated against different Gram-positive and Gram-negative bacteria using agar diffusion method
Electronic supplementary materialThe online version of this article (doi:10.1186/s13065-017-0268-2) contains supplementary material, which is available to authorized users.
“…The Co–O bond distances of 2.117(8), 2.128(6), 2.220(10) and 2.220(10) Å are similar to reported values [39–47]. Co–N bond distances of 2.090(7) and 2.100(7) Å are also similar to reported values [39–48]. Selected angles and distances are listed in Table 1.Fig.…”
Four novel complexes [Co(H2O)4(sul)2] 1, [Co(2-ampy)2(sul)2] 2, [Co(H2O)2(1,10-phen) (sul)2] 3 and [Co(2,9-dimephen)(sul)2] 4 (sul = sulindac, 2-ampy = 2-amino pyridine, 1,10-phen = 1,10-phenanthroline and 2,9-dimeph = 2,9-dimethyl-1,10-phenanthroline) were prepared and characterized by IR, UV–Visible spectroscopy and magnetic properties. The crystal structures of complexes 1 and 4 were determined by single-crystal X-ray diffraction. In-vitro anti-bacterial activity for the prepared complexes against Gram-positive (Staphylococcus epidermidis, Staphylococcus aureus) and Gram-negative (Bordetella, Escherichia coli) bacteria and Yeast species (Saccharomyces and Candida) were performed using agar well-diffusion method. Only complex 4 showed reasonable activity against yeast. All compounds showed more anti-bacterial activity against Gram-positive bacteria than Gram-negative.Graphical abstractThis work reports synthesis, crystallographic, spectroscopic studies and biological activity of new cobalt(II) complexes with bioactive mixed sulindac and nitrogen-donor ligands. The crystal structures of complexes 1 and 4 were determined using single-crystal X-ray diffraction.
In-vitro anti-bacterial activity of the prepared complexes and their parent ligands were investigated against different Gram-positive and Gram-negative bacteria using agar diffusion method
Electronic supplementary materialThe online version of this article (doi:10.1186/s13065-017-0268-2) contains supplementary material, which is available to authorized users.
“…1760-1680 cm À1 . Upon complexation to a metal center, this m(C@O) band is red-shifted and splits to two new bands, asymmetric m as (COO À ) and symmetric m s (COO À ) stretches appear in the regions 1650-1550 and 1440-1335 cm À1 respectively [29,30].…”
“…[45,46] The Zn-N bond lengths formed with the phenanthroline ligand [2.107(11) and 2.174(11) Å] are similar to those found in other pentacoordinate phenanthroline complexes. [47][48][49][50] In these cases the interactions largely responsible for the crystal packing are the C-H···O hydrogen-bonding interactions established between the oxygen atoms of the SO 2 groups of the ligands (H 2 L) and different C-H groups, with π-π stacking interactions also evident between the nitrogenated co-ligands. The C-H···O interactions are similar to those already discussed for the free ligand and for the other complexes, although in these cases the interactions are established in three dimensions (see data in Table S1).…”
Section: Crystal Structures Of [Col(phen)] (5) and [Znl(phen)] (7)mentioning
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