Synthesis, crystal structures and toxicity of bicadmium(ii) complexes with macrocyclic, hexaaza-bearing, hydroxyethyl pendants

Gao, Jian; Xu, Xing‐You; Wei-xing, MA; Wang, Mingyan; Song, Huan; Yang, Xin; Lu, Lude; Wang, Xin

doi:10.1080/00958970412331298784

Cited by 14 publications

(3 citation statements)

References 14 publications

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“…In recent years, oxidation of organic compounds by copper and its complexes has attracted significant attention of scientists [11] and huge demand as a mild catalyst has been created [12]. Copper complexes have surely exhibited a wide range of pharmacological activities [13]. The present study explains the spectroscopic studies on the adduct formation using well-known flavonoid biomolecules Q, which are characterized using various modern analytical techniques.…”

Section: Introductionmentioning

confidence: 94%

Green synthesis, characterizations, and in vitro biological evaluation of Cu (II) complexes of quercetin with N ^ N ligands

Srivastava¹,

Mishra²,

Tiwari³

2021

J App Biol Biotech

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The primary goal of this research was to focus on the synthesis of two complex compounds, i.e., [{Cu (Q) (2, 2ʹ-bipyridal Bpy ) (acetate)} complex 1] and [{Cu (Q) (1, 10-phenanthroline Phen ) (acetate)} complex 2], which were found soluble in dimethyl sulfoxide and dimethylformamide. Complex 1 and 2 were incorporated and secluded as sole items in significant returns (>97%) by granulating strong fixing, i.e., quercetin (Q), copper acetate supported with Bpy, and Phen without any solvent. Both the synthesized compounds were characterized spectroscopically (Fourier transformation infrared spectroscopy, ultraviolet-visible, high-resolution mass spectroscopy, and elemental analysis) and biological (antioxidant, antibacterial, cytotoxicity, enzymatic, and nonenzymatic assay) evaluation was carried out against microbes. IC 50 of synthesized complex 1 and 2 was determined as 168.97 and 125.932 µg/ml, respectively, whereas Q was found to be 38.1427 µg/ml. Minimum inhibitory concentration of both complexes (1,2) was determined as 25.83, 50.37, and 6.35, 13.74 µg/ml, respectively, in both strains (Escherichia coli and Staphylococcus aureus). Cell proliferation activity was carried out by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT) assay method in both microbes and MG-63 cells. Treated organisms were researched for enzymatic (superoxide dismutase and catalase) and nonenzymatic (glutathione) assays, alongside lipid peroxidation and protein leakage tests. MTT assay was carried out in both microbes and MG-63 cells (toxicity was found to be safe up to 500 ppm compared to Q).

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Section: Introductionmentioning

confidence: 94%

Green synthesis, characterizations, and in vitro biological evaluation of Cu (II) complexes of quercetin with N ^ N ligands

Srivastava¹,

Mishra²,

Tiwari³

2021

J App Biol Biotech

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“…[12] For comparison, the antimicrobial activity of Cu(ClO 4 ) 2 . 6H 2 O and imidazole were also tested.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Synthesis, Crystal Structure and Properties of a New Mixed Ligand Copper(II) Complex [Cu(imH) (aepa)](ClO₄)₂ (imH=imidazole, aepa=N‐(2‐aminoethyl)‐1,3‐propylamine)]

Gao³

et al. 2006

Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-

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“…Toxicity of the complexes was evaluated by testing antimicrobial activity to bacterial strands using the agar diffusion method as described in the literature [16]. 2)) is 23.7 .…”

Section: Antimicrobial Activity Determinationmentioning

confidence: 99%

Synthesis, structure and antimicrobial study of two copper(II) complexes derived from paeonol and R-NH-propyldiamine

Gao²,

et al. 2007

Journal of Coordination Chemistry

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Two new copper(II) complexes were synthesized from 2-hydroxyl-4-methoxyacetophone with R-NH-CH 2 -CH 2 -CH 2 -NH 2 (for complex 1, R ¼ H; complex 2, R ¼ C 6 H 5 -CH 2 -) in the presence of Cu 2þ . Crystals of 1 were monoclinic, space group P2 1 /n, with a ¼ 12.6408(10) Å , b ¼ 7.4063(6) Å , c ¼ 16.8863(14) Å and ¼ 93.3590(10) , complex 2 crystals were triclinic, space group P 1 with a ¼ 7.561(3) Å , b ¼ 10.680(4) Å , c ¼ 13.868(5) Å and ¼ 97.389(6) , ¼ 95.240(6) , ¼ 101.206(6) . Both Cu(II) atoms were four-coordinate with distorted square-planar geometry. The toxicity of 1 and 2 were evaluated by testing antimicrobial activity against bacterial strands.

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Synthesis, crystal structures and toxicity of bicadmium(ii) complexes with macrocyclic, hexaaza-bearing, hydroxyethyl pendants

Cited by 14 publications

References 14 publications

Green synthesis, characterizations, and in vitro biological evaluation of Cu (II) complexes of quercetin with N ^ N ligands

Green synthesis, characterizations, and in vitro biological evaluation of Cu (II) complexes of quercetin with N ^ N ligands

Synthesis, Crystal Structure and Properties of a New Mixed Ligand Copper(II) Complex [Cu(imH) (aepa)](ClO₄)₂ (imH=imidazole, aepa=N‐(2‐aminoethyl)‐1,3‐propylamine)]

Synthesis, structure and antimicrobial study of two copper(II) complexes derived from paeonol and R-NH-propyldiamine

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Synthesis, crystal structures and toxicity of bicadmium(ii) complexes with macrocyclic, hexaaza-bearing, hydroxyethyl pendants

Cited by 14 publications

References 14 publications

Green synthesis, characterizations, and in vitro biological evaluation of Cu (II) complexes of quercetin with N ^ N ligands

Green synthesis, characterizations, and in vitro biological evaluation of Cu (II) complexes of quercetin with N ^ N ligands

Synthesis, Crystal Structure and Properties of a New Mixed Ligand Copper(II) Complex [Cu(imH) (aepa)](ClO4)2 (imH=imidazole, aepa=N‐(2‐aminoethyl)‐1,3‐propylamine)]

Synthesis, structure and antimicrobial study of two copper(II) complexes derived from paeonol and R-NH-propyldiamine

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Synthesis, Crystal Structure and Properties of a New Mixed Ligand Copper(II) Complex [Cu(imH) (aepa)](ClO₄)₂ (imH=imidazole, aepa=N‐(2‐aminoethyl)‐1,3‐propylamine)]