Synthesis, nematocidal activity and docking study of novel chiral 1-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide derivatives

Synthesis and in vivo fungicidal activity of some new quinoline derivatives against rice blast

“…The fluorine atom with a small radius and strong electronegativity has simulation, electronic, blocking, and penetration effects. Fluorine atoms are frequently introduced into herterocycles to obtain strong bioactivity in medicinal chemistry and pesticide chemistry.…”

Synthesis and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against Aedes aegypti

“…A number of studies in the literature have reported that many commercial pesticides contain pyrimidine, urea or diacylhydrazine moiety, such as pirimiphos‐methyl, monosulfuron, diflubenzuron and RH‐5849 (Scheme ). In line with our continued efforts to synthesize bioactive lead compounds for crop protection, the title compounds were designed using the method of active substructure combination. Our original strategy is depicted in Scheme .…”

Synthesis, crystal structure, and optical properties of fluorinated poly(pyrazole) ligands andin silicoassessment of their affinity for volatile organic compounds

“…Pyrazole and its derivatives have been extensively studied for their wide biological activities, [1][2][3] including antibacterial, 4 antifungal, [5][6][7][8] and insecticidal [9][10][11] properties. Furthermore, pyrazoles have been intensively employed as nitrogen-donor ligands in coordination chemistry.…”