1967
DOI: 10.1002/anie.196700821
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Synthesis of 7‐Amino‐6‐methoxy‐5,8‐quinolinedione

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1977
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Cited by 15 publications
(6 citation statements)
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“…Nevertheless, some examples of its substitution by N ‐nucleophiles are known in heterocycles such as 1,2,4‐triazine 1‐oxide and pyridazin‐3(2 H )‐one . Unusual examples of the relative nucleofugality are described for 7‐bromo‐6‐methoxy‐5,8‐quinolinedione and 4‐chloro‐8‐methoxy‐5‐nitroquinoline , because in these compounds, the methoxy group rather than halogen atoms was subjected to substitution by the amino group. Previously, we have shown the possibility to replace the alkoxy groups in 1,3,7‐triazapyrene ring by aryl amino and acyl amino groups .…”
Section: Introductionmentioning
confidence: 99%
“…Nevertheless, some examples of its substitution by N ‐nucleophiles are known in heterocycles such as 1,2,4‐triazine 1‐oxide and pyridazin‐3(2 H )‐one . Unusual examples of the relative nucleofugality are described for 7‐bromo‐6‐methoxy‐5,8‐quinolinedione and 4‐chloro‐8‐methoxy‐5‐nitroquinoline , because in these compounds, the methoxy group rather than halogen atoms was subjected to substitution by the amino group. Previously, we have shown the possibility to replace the alkoxy groups in 1,3,7‐triazapyrene ring by aryl amino and acyl amino groups .…”
Section: Introductionmentioning
confidence: 99%
“…This is due to the fact that quinone derivatives are widely used as fungicides [1,2] and antibacterial agents [2][3][4]. Also a large number of chemicals derived from quinone as the basic subunit exhibit prominent pharmacological applications such as antimalarial [5] and herbicidal activity [6].…”
Section: Introductionmentioning
confidence: 99%
“…Quinoline derivatives are widely used as fungicides [1][2][3] and antibacterial agents [4][5][6] . The -lctam antibiotics continue to represent a major class of clinically very important and commercially valuable therapeutic agents [7][8][9] .…”
Section: Introductionmentioning
confidence: 99%