The reaction of some newly synthesised compound 2, 4-diamino-lH-benz[g]quinolino-5,l0-dione 3-ethyl carboxylate 1 and 2,4-diamino-l ,2,3-trihydropiperpdino[2,3-b]benz[g]-1 ,2,3,4-tetrahydroquinolines-5,6,11-trione 3 ethylcarboxylate 2 with different aromatic aldehyde afforded the corresponding new Schiff bases derivatives 3a-c, 4a-c. The cycloaddition reaction of 3a-c, 4a-c with chloroacetyl chloride and thioglycolic acid give new isolated β -Lactams and thiazlidinone derivatives 5a-c, 7a-c and 6a-c, 8a-c. Compound 1, 2 undergo hydrolysis by NaOH to give carboxylic compound 9,10 which react with different aromatic aldehyde to give new Schiff bases 11a-c and 12a-c. The cycloaddition reaction of 11a-c, 12a-c with chloroacetylchloride and/or mercaptoacetic acid to give 13a-c, 15a-c and 14a-c, 16a-c.