Synthesis of NIR-Responsive NaYF<sub>4</sub>:Yb,Er Upconversion Fluorescent Nanoparticles Using an Optimized Solvothermal Method and Their Applications in Enhanced Development of Latent Fingerprints on Various Smooth Substrates

et al. 2017

Adv Funct Materials

Self Cite

214

159

This review presents an overview on the application of latent fingerprint development techniques in forensic sciences. At present, traditional developing methods such as powder dusting, cyanoacrylate fuming, chemical method, and small particle reagent method, have all been gradually compromised given their emerging drawbacks such as low contrast, sensitivity, and selectivity, as well as high toxicity. Recently, much attention has been paid to the use of fluorescent nanomaterials including quantum dots (QDs) and rare earth upconversion fluorescent nanomaterials (UCNMs) due to their unique optical and chemical properties. Thus, this review lays emphasis on latent fingerprint development based on QDs and UCNMs. Compared to latent fingerprint development by traditional methods, the new methods using fluorescent nanomaterials can achieve high contrast, sensitivity, and selectivity while showing reduced toxicity. Overall, this review provides a systematic overview on such methods.

Section: Latent Fingerprint Development Using Rare Earth Upconversmentioning

confidence: 99%

Fluorescent Nanomaterials for the Development of Latent Fingerprints in Forensic Sciences

et al. 2017

Adv Funct Materials

Self Cite

214

159

“…Normally, UCNPs synthesized through the two most frequently used strategies are capped by oleate or oleylamine, 40 …”

Section: Modification Strategies Of Ucnpsmentioning

confidence: 99%

Upconversion nanocomposites for photo-based cancer theranostics

Zeng

et al. 2016

J. Mater. Chem. B

Lanthanide ions doped upconversion nanoparticles (UCNPs) are known to be able to convert the long-wavelength excitation light (usually 980 nm) into high-energy ultraviolet (UV) or visible emissions, and they have attracted significant attentions because of their distinct photochemical properties including sharp emission bands, low autofluorescence, high tissue penetration depth, inert to ambient interference and minimized photodamage to tissues. Untill now, UCNPs have shown great potentials in various realms including bioimaging, biosensing and biomedical applications. Especially in recent years, UCNPs based nanocomposites have been found to be promising tools for multi-modal imaging and low-invasive photo-based therapy of tumors. In this review, we summarize the recent achievement and progress of UCNPs based multifunctional nanoplatforms for bioimaging and cancer phototheranostics, including photodynamic therapy (PDT) and photothermal therapy (PTT). Furthermore, some emerging trends, future directions as well as challenges in this rapidly growing field are discussed.

“…Their experimental results showed that these upconversion-based nanoprobes could be used as fluorescent labels of tumors in bioimaging applications. Moreover, it is impressive that upconversion nanoparticles can be also applied to the detection of trace organic dyes such as Rhodamine B and sodium fluorescein in living organisms based on a LRET process [34][35][36], as well as latent fingerprint development in forensic sciences [37,38].…”

Section: Introductionmentioning

confidence: 99%

Identification on Mantle Cell Lymphoma Using CD20 and CD5 Coupled Upconversion Fluorescent Nanoprobes

Zhang

Gao

Journal of Nanomaterials

et al. 2018

In order to determine a particular tumor cell via nanomaterials, we introduce the preparation of CD20 and CD5 coupled nanoprobes (denoted as CD20 and CD5 nanoprobes for convenience) and an application in identification of mantle cell lymphoma (MCL) from B-cell lymphoma. In this work, CD20 and CD5 nanoprobes were prepared by selectively oxidizing the carbon-carbon double bonds of oleate ligands on the surfaces of NaYF 4 :Yb 3+ ,Tm 3+ and NaYF 4 :Yb 3+,Er 3+ nanoparticles and, respectively, coupling carboxyl groups on the particles' surfaces with CD20 and CD5 monoclonal antibodies through EDC/NHS crosslinking agents. After in situ hybridized Jeko-1 cells and Raji cells as a reference with CD20 and CD5 nanoprobes, in vitro double-color upconversion fluorescence imaging of Jeko-1 cells was demonstrated through visualization of blue and green fluorescence under a 980 nm laser excitation. Moreover, in vivo upconversion fluorescence imaging of the transplanted cancer model was also measured. These experimental results indicate that Jeko-1 cells have been specifically labeled by CD20 and CD5 nanoprobes. It is therefore concluded that CD20 and CD5 nanoprobes could be used to specially differentiate mantle cell lymphoma (MCL) from B-cell lymphoma.