Synthesis of well-defined star, star-block, and miktoarm star biodegradable polymers based on PLLA and PCL by one-pot azide–alkyne click reaction

Abstract

Star, star-block, and miktoarm star biodegradable polymers were synthesized by an “arm-first” strategy, ring-opening polymerization and one-pot azide-alkyne click reaction.

Miktoarm star‐shaped poly(lactic acid) copolymer: Synthesis and stereocomplex crystallization behavior

“…Therefore, many unique SC crystallization behaviors may occur when scPLA is combined with star polymers. Miktoarm star‐shaped copolymers, also called asymmetric star copolymers, heteroarm star copolymers, or simply miktoarm copolymers, are star‐shaped copolymers with certain amount of different polymer arms radiating from a core . In our previous work, we have discussed the SC crystallization behaviors of linear/linear, linear/star‐shaped, and star‐shaped/star‐shaped blends .…”

Click chemistry strategies for the accelerated synthesis of functional macromolecules

“…712 Star BCPs were also prepared by grafting alkyne-terminated arms including PCL-b-poly-L-lactide (PLLA)-alkyne onto a tetra-azide functionalized core via CuAAC (Figure 44). 713 Nitrile N-oxide based click chemistry was employed for preparing 3,4,or 6 arm star polymers by rapid coupling of PEG arms with highly reactive CN + -O À chain ends in the presence of a multi-allylfunctionalized core under catalyst-free and solvent-free conditions. 82 Gadwal reported star polymer synthesis by clicking a thiol-terminated PEG to a tri-epoxide core through thiol-epoxy chemistry.…”

“…The simplest approach is one-pot conjugation of two different arm polymers, which are in 1:1 ratio, to the core. For example, PCL 2 PLLA 2 713 and PS 2 PB 2 712 4-arm miktoarm star polymers were synthesized via CuAAC coupling of arm polymers to a tetrafunctional core while maintaining a 1:1 molar ratio of two different arms. It should however be noted that one-pot coupling-to approach poses difficulties in determining the composition of miktoarm star polymers accurately.…”

“…Coupling‐to synthetic route of star (4sPCL, 4sPLLA), star‐block (4sPCL‐ b ‐PLLA), and miktoarm star polymers (PCL 2 PLLA 2 ) by one‐pot CuAAC 713 [Color figure can be viewed at wileyonlinelibrary.com]…”

BODIPY-based fluorescent polymeric probes for selective detection of Fe3+ ions in aqueous solution

“…In order to introduce sulfur elements and unsaturated bonds that can bind metal ions into the main chain, click reaction is a good method. And the click reaction can easily and efficiently obtain well-defined polymers [20]. The characteristics of an ideal click reaction include high yield, mild reaction conditions, harmless byproducts, and insensitivity to oxygen and water [21].…”