Synthesis, spectral characterization and biological studies of transition metal(II) complexes with triazole Schiff bases

Hanif, Muhammad Asif; Chohan, Zahid H.

doi:10.1002/aoc.2936

Cited by 33 publications

(16 citation statements)

References 58 publications

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“…Concentraion, µg/mL Aspergillus niger Fusarium oxysporum Candida albicans 43,44 The morphological changes involved malformation and incomplete separation of the cells; HL 3 -treated B. cereus showed significant short irregular rods with multiple cross walls (Table 7 and S. aureus showed some filament-like cells rather than normal cocci cells (Figure 3). These malformations and multiple cross walls can be associated with teichoic acids lacking D-alanine, in cell walls, when DltA is inhibited.…”

Section: Ligands Amentioning

confidence: 99%

Allyl rhodanine azo dye derivatives: Potential antimicrobials target d‐alanyl carrier protein ligase and nucleoside diphosphate kinase

Abou‐Dobara

Omar

Diab

et al. 2018

J of Cellular Biochemistry

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3-Allyl-5-(4-arylazo)-2-thioxothiazolidine-4-one (HL ) ligands (where n = 1 to 3) were hypothesized to have antimicrobial activities mediated through inhibition of new antimicrobial targets. The ligands (HL ) were synthesized and characterized by infrared (IR) and H nuclear magnetic resonance ( H NMR) spectra. The ligands (HL ) were in silico screened to their potential inhibition to models of d-alanyl carrier protein ligase (DltA) (from Bacillus cereus, PDB code 3FCE) and nucleoside diphosphate kinase (NDK) (from Staphylococcus aureus; PDB code 3Q8U). HL ligand has the best energy and mode of binding to both NDK and DltA, even though its binding to DltA was stronger than that to NDK. In antimicrobial activity of HL ligand, morphological and cytological changes in HL -treated bacteria agreed with the in silico results. The HL ligand showed significant antimicrobial activity against B. cereus, S. aureus, and Fusarium oxysporium. The HL -treated bacterial cells appeared malformed and incompletely separated. Its cell walls appeared electron-lucent and ruptured. They contained more mesosomes than normal cells. It was found that the HL ligand represented as a bactericide against B. cereus and S. aureusby blocking target DltA, and may target NDK.

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Section: Ligands Amentioning

confidence: 99%

Allyl rhodanine azo dye derivatives: Potential antimicrobials target d‐alanyl carrier protein ligase and nucleoside diphosphate kinase

Abou‐Dobara

Omar

Diab

et al. 2018

J of Cellular Biochemistry

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“…Azole-based compounds, 1,2,4-triazole and its derivatives [11,[17][18][19][20][21][22][23][24] [13,17,[27][28][29]), DATr increases nitrogen content and improves the possibility for hydrogen-bonding to favor enhancing stabilities of complexes.…”

Section: Introductionmentioning

confidence: 99%

A 1D cadmium complex with 3,4-diamino-1,2,4-triazole as ligand: synthesis, molecular structure, characterization, and theoretical studies

Jin

Yin

et al. 2015

Journal of Coordination Chemistry

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2015): A 1D cadmium complex with 3,4-diamino-1,2,4-triazole as ligand: Synthesis, molecular structure, characterization, and theoretical studies, Journal of Coordination Chemistry, An energetic complex, [Cd 2 (μ-Cl) 4 Cl 2 (DATr) 2 ] n (1) (DATr = 3,4-diamino-1,2,4-triazole), was synthesized from DATr·HCl and cadmium(II) chloride. The product was characterized by Fourier transform-infrared spectroscopy (FT-IR) analysis, elemental analysis, X-ray diffraction analysis, and differential scanning calorimeter (DSC) analysis. The central cadmium(II) ions in 1 are six-coordinate twisted octahedral structures, which are made up of 1D chains linked by bridging chlorides. The results of the DSC analysis suggest the temperature of decomposition to be above 503.15 K. Furthermore, the kinetic properties of decomposition are studied by Kissinger's and Ozawa-Doyle's methods, and the calculated average activation is 166.5 kJ·mol -1 , which means the complex is stable under normal conditions. In addition, the energy of combustion was measured by oxygen bomb calorimetry. The critical temperature of thermal explosion and parameters of thermodynamics of 1 were calculated. The periodic structure of 1 has been calculated based on the density functional theory. The theoretical results explain the electronic structure and thermal dynamic properties.

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“…The band at about 295 nm for the Ni(L 2 ) 2 complex is related to ligand‐to‐metal charge transfer . Absorption bands in the visible region, 503 and 586 nm for Ni(L 2 ) 2 and Cu(L 2 ) 2 , respectively, are due to d–d transitions (Figure ) …”

Section: Resultsmentioning

confidence: 99%

Design and synthesis of novel thiourea metal complexes with controllable antibacterial properties

Rakhshani

Rezvani

Dušek

et al. 2018

Applied Organom Chemis

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A new bidentate O,S donor thiourea ligand (L 1 ), namely N-(2-hydroxyethyl)-N′-2-chlorobenzoylthiourea, and its oxazolidine derivative (L 2 ) were synthesized.Derivative L 2 was used for the preparation of Ni(L 2 ) 2 and Cu(L 2 ) 2 complexes. The compounds were investigated using X-ray crystallography and Fourier transform infrared, 1 H NMR and UV-visible spectroscopies. Single-crystal Xray analysis showed strong hydrogen bonding interactions between carbonyl oxygen and N(10) ─ H in the L 1 ligand. In addition, the antibacterial activities of these compounds were evaluated against Gram-positive and Gram-negative bacteria, measured using the colony count method. The Cu(L 2 ) 2 complex exhibited a significant antibacterial activity while the activity of the other compounds was much lower. Finally, the relationship between the structure and antibacterial properties of these compounds was investigated using highest occupied and lowest unoccupied molecular orbital energies calculated by density functional theory method based on the 6-31G*/LANL2DZ basis set.

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Synthesis, spectral characterization and biological studies of transition metal(II) complexes with triazole Schiff bases

Cited by 33 publications

References 58 publications

Allyl rhodanine azo dye derivatives: Potential antimicrobials target d‐alanyl carrier protein ligase and nucleoside diphosphate kinase

Allyl rhodanine azo dye derivatives: Potential antimicrobials target d‐alanyl carrier protein ligase and nucleoside diphosphate kinase

A 1D cadmium complex with 3,4-diamino-1,2,4-triazole as ligand: synthesis, molecular structure, characterization, and theoretical studies

Design and synthesis of novel thiourea metal complexes with controllable antibacterial properties

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