Synthesis, spectral properties, DNA binding interactions and DNA cleavage studies of lanthanide (III) complexes of 2-acetylpyridine acetoylhydrazone: the X-ray crystal structure of 10-coordinate Ce (III) and Sm (III) complexes

Synthesis, X-ray crystal structure, DNA binding and Nuclease activity of lanthanide(III) complexes of 2-benzoylpyridine acetylhydrazone

“…Selected bond angles ( • ) for the structure of 2. N(1)-Ce(1)-N(2) 57.13(7) N(6)-Ce(1)-N(5) 58.46(8) O(1)-Ce(1)-N(1) 115.63(7) O(2)-Ce(1)-N(6) 117.70(8) O(1)-Ce(1)-N(2) 58.50(7) O(2)-Ce(1)-N(5) 59.31(8) O(7)-Ce(1)-N(1) 80.14(10) O(6)-Ce(1)-N(6) 73.76(9) O(6)-Ce(1)-N(1) 143.06(9) O(7)-Ce(1)-N(6) 138.05(9) O(3)-Ce(1)-N(1) 68.99(9) O(3)-Ce(1)-N(6) 74.46(9) O(4)-Ce(1)-N(1) 74.66(9) O(4)-Ce(1)-N(6) 71.55(8) O(2)-Ce(1)-N(1) 70.87(8) O(1)-Ce(1)-N(6) 75.77(8) N(6)-Ce(1)-N(1) 141.09(9) O(2)-Ce(1)-O(1) 151.64(9) and O(2), O(6), N(6), O(3) define the other face.Azomethine nitrogen atoms are on the bicapped positions, which are similar to previously reported 10-coordinated lanthanide (III) complexes 17,31. …”

“…32,33 However some carbon-carbon interactions are present which comprises 1.7% and 2.4% of the total Hirshfed surface area of La and Ce complexes. We have compared Hirshfeld surface analysis of some related lanthanide complexes with similar ligands 16,17 and gathered the results in Table 8.…”

“…However, to the best of our knowledge, much attention was not paid to explore the DNA interaction and nuclease activities of rare earth metal complexes * For correspondence derived from pyridine based hydrazones. Recently, we have reported 16,17 synthesis, spectral properties and DNA binding and nuclease activity of lanthanide(III) complexes of pyridine hydrazones. In the light of the above, and in continuation of our previous work, herein we report synthesis, crystal structure, DNA binding and cleavage activity of La(III) and Ce(III) complexes with 2-benzoylpyridine acetyl hydrazone (BPAH).…”

Spectral characterization and DNA binding properties of lanthanide(III) complexes with 2-acetylpyridine isonicotinoylhydrazone (APINH)

“…In the spectra of lanthanide complexes, the band due to N-H stretching vibration of metal free ligand is not affected precluding the involvement of NH group in coordination. The appearance of NH band in the IR spectra of complexes suggests that the ligand remains in keto form in coordination [34]. Strong bands observed at 1668 and 1623 cm -1 are respectively assigned to ν C=O and ν C=N vibrations.…”