Synthesis, structural and larvicidal studies of some triorganotin 2-(p-chlorophenyl)-3-methylbutyrates

Eng, George; Song, Xueqing; Zapata, Alejandra; Dios, Angel C. de; Casabianca, Leah B.; Pike, Robert D.

doi:10.1016/j.jorganchem.2006.11.030

Cited by 60 publications

(31 citation statements)

References 24 publications

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“…This result is similar to those for other tricyclohexyltin carboxylates. 18 The results of the infrared studies are in agreement with the Mössbauer data. In summary, all the complexes are pentacoordinated, with the exception of the tricyclohexyl derivative, which is four-coordinated in the solid state.…”

Section: Main Group Metal Compoundssupporting

confidence: 81%

Synthesis, larvicidal, QSAR and structural studies of some triorganotin 2,2,3,3‐tetramethylcyclopropanecarboxylates

Song

Zapata

Hoerner

et al. 2007

Applied Organom Chemis

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A series of triorganotin 2,2,3,3-tetramethylcyclopropanecarboxylates, where R = methyl, ethyl, npropyl, n-butyl, phenyl and cyclohexyl, have been synthesized. Elemental analysis, Mössbauer, infrared and NMR spectroscopies were used to characterize their structures. Based on the spectroscopic results, all the complexes in the solid state with the exception of the tricyclohexyl compound were found to be five-coordinated, while the tricyclohexyltin derivative was determined to be fourcoordinated. Based on the NMR results, all the complexes in solution have a tetrahedral configuration. Larvicidal activities of the complexes were evaluated against the second instar stage of the Aedes aegypti, Anopheles stephensi and Culex pipiens quinquefasciatus mosquitoes. The toxicity results indicated that this series of triorganotins are effective larvicides against all three species of larvae. In addition, quantitative structure-activity relationships (QSARs) were also developed for each species of larvae.

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Section: Main Group Metal Compoundssupporting

confidence: 81%

Synthesis, larvicidal, QSAR and structural studies of some triorganotin 2,2,3,3‐tetramethylcyclopropanecarboxylates

Song

Zapata

Hoerner

et al. 2007

Applied Organom Chemis

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“…The toxicity results in the current study are similar to other series of triorganotins evaluated. [10,11,14] The results from the current study indicate that there are no significant differences in the toxicity of the compounds towards the different species of mosquito larvae based on a single-factor analysis of variance (ANOVA). Similar results were observed for the methylbutyrates [10] and cyclopropanecarboxylates [11] series.…”

Section: Toxicity Resultsmentioning

confidence: 70%

“…Previously, modified fragments of pyrethrin such as a methylbutyrate and/or cyclopropanecarboxylate group have been incorporated into various triorganotins and their activities were evaluated against various mosquito larvae. [10,11] Chrysanthemic acid (2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid) is another active fragment in the first synthetic pyrethroid: allethrin. [9] Thus a series of modified triorganotin chrysanthemumates have been synthesized and their efficacies against various species of mosquito larvae are reported herein.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, structural and larvicidal studies of a series of triorganotin chrysanthemumates

Zapata

Mclean

Hernández

et al. 2011

Applied Organom Chemis

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A series of triorganotin chrysanthemumates (2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylates) (R 3 SnO 2 CC 9 H 15 ) where R = methyl, ethyl, n-butyl and phenyl was synthesized. The solid state structures were deduced using infrared (IR) and Mössbauer spectroscopies. The spectroscopic results indicated that all the compounds were found to be five-coordinated in the solid state. Based on the NMR results, all the compounds are tetrahedral in solution. Larvicidal activities of the compounds were evaluated against the second instar stage of Aedes aegypti, Anopheles stephensi and Culex pipiens quinquefasciatus mosquitoes. The toxicity results indicated that these compounds of triorganotins were effective larvicides against all three species of larvae.

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“…The range of LC 50 values of triorganotin 2-(p-chlorophenyl)-3-metylbutyrate was 0.32-3.13 ppm (Eng et al, 2007). This value indicated that compound B and C were more effective as larvicide against Ae.…”

Section: Discussionmentioning

confidence: 90%

The Effectiveness of Organotin (IV) Benzylisopropyldithiocarbamate Compounds as Insecticide Against <i>Aedes Aegypti</i> Linn (Diptera: Culicidae) in Laboratory

Awang¹,

Kosnon

Othman³

et al. 2012

American Journal of Applied Sciences

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Problem statement:The widespread use of insecticides had resulted in insecticide resistance of vectors of dengue as well as polluting the environment. Organotin (IV) compounds had the potential to be developed as the insecticides to overcome the existing problem. Approach: The aim of this study was to examine the insecticidal effects which were larvicidal and adulticidal effects of organotin (IV) benzylisopropyldithiocarbamate compounds against Aedes Aegypti Linn. In laboratory larvicidal bioassay test of a series of three organotin (IV) benzylisopropyldithiocarbamate compounds on third instar larvae of Aedes Aegypti had been carried out. Results: The study was found that compound B showed the best larvicidal effect with the LC 50 and LC 90 values of 0.004 ppm and 0.007 ppm, respectively. Compound C was also displayed good larvicidal effect with the LC 50 and LC 90 values of 0.029 ppm and 0.108 ppm, respectively. While, compound A was shown the least larvicidal effect with the LC 50 and LC 90 values of 0.404 ppm and 0.749 ppm, respectively. Further testing was conducted on compound B on adults of Aedes ageypti female to investigate its adulticidal property. The result showed that compound B displayed good adulticidal activity with LC 50 dan LC 90 of 4.277 ppm and 27.653 ppm, respectively. Conclusion: Compound B is the most effective compound among three organotin (IV) benzylisopropyldithiocarbamate compounds tested against the dengue vector Aedes Aegypti and has potential to be explored as an insecticide to control the spread of dengue fever.

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Synthesis, structural and larvicidal studies of some triorganotin 2-(p-chlorophenyl)-3-methylbutyrates

Cited by 60 publications

References 24 publications

Synthesis, larvicidal, QSAR and structural studies of some triorganotin 2,2,3,3‐tetramethylcyclopropanecarboxylates

Synthesis, larvicidal, QSAR and structural studies of some triorganotin 2,2,3,3‐tetramethylcyclopropanecarboxylates

Synthesis, structural and larvicidal studies of a series of triorganotin chrysanthemumates

The Effectiveness of Organotin (IV) Benzylisopropyldithiocarbamate Compounds as Insecticide Against <i>Aedes Aegypti</i> Linn (Diptera: Culicidae) in Laboratory

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