Synthesis, structural characterization and biological activities of metal(II) complexes with Schiff bases derived from 5-bromosalicylaldehyde: Ru(II) complexes transfer hydrogenation

Buldurun, Kenan; Turan, Nevin; Savcı, Ahmet; Çolak, Naki

doi:10.1016/j.jscs.2018.06.002

Cited by 65 publications

(24 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Ruthenium has chemical and industrial applications, which include corrosion resistance when mixed with titanium, as platinum alloys, as catalysts, and as superconductor when alloyed with molybdenum at a temperature below 10 K. Ruthenium, rhodium, and iridium complexes are the most active and chosen hydrogen transfer catalysts. Among the three complexes of iridium, rhodium, and ruthenium, ruthenium complexes are superior due to their low cost and high activity [101]. Of all ruthenium compounds, arene ruthenium compounds have robust metal-organic molecules which are essential for organometallic chemistry development [101].…”

Section: Rhodiummentioning

confidence: 99%

“…Among the three complexes of iridium, rhodium, and ruthenium, ruthenium complexes are superior due to their low cost and high activity [101]. Of all ruthenium compounds, arene ruthenium compounds have robust metal-organic molecules which are essential for organometallic chemistry development [101]. ree major characteristics make ruthenium compounds suitable for medical applications such as ability to imitate iron to bind to certain biological molecules, slow rate of ligand exchange, and the variable oxidation states [102,103].…”

Section: Rhodiummentioning

confidence: 99%

See 1 more Smart Citation

Developments in Platinum-Group Metals as Dual Antibacterial and Anticancer Agents

Odularu

Ajibade

Mbese

et al. 2019

Journal of Chemistry

View full text Add to dashboard Cite

Platinum-group (PG) complexes have been used as antibacterial and anticancer agents since the discovery of cisplatin. The science world still requires improvement on these complexes because of multidrug and antineoplastic resistances. This review observes discoverers and history of these platinum-group metals (PGMs), as well as their beneficial applications. The focus of this study was biological applications of PGMs in relation to human health. Sandwich and half-sandwich PGM coordination compounds and their metal nanoparticles give improved results for biological activities by enhancing efficient delivery of both antibacterial and anticancer drugs, as well as luminescent bioimaging (biomarkers) for biological identifications.

show abstract

Section: Rhodiummentioning

confidence: 99%

Section: Rhodiummentioning

confidence: 99%

Developments in Platinum-Group Metals as Dual Antibacterial and Anticancer Agents

Odularu

Ajibade

Mbese

et al. 2019

Journal of Chemistry

View full text Add to dashboard Cite

show abstract

“…Antioxidants have found widespread practical application in chemistry, chemical engineering, food industry and pharmacy. Multiple contributions are provided on research of various natural compounds [1][2][3][4], their synthetic analogues [5][6][7][8][9][10][11][12] and botanicals extracts [13][14][15] antioxidative activity. Antioxidative therapy is a way of treating various diseases which develop significantly through free-radical processes [16,17].…”

Section: Introductionmentioning

confidence: 99%

Antiradical activity and bioprediction of o-and p-hydroxybenzoic acid hydrazide derivatives

Сатпаева¹,

Нуркенов²,

Schulgau³

et al. 2020

Bull. of the Kar. Univ. "Chem". Ser.

View full text Add to dashboard Cite

Antiradical activity and bioprediction of o-and p-hydroxybenzoic acid hydrazide derivatives This article provides results of evaluation of synthesized biologically active substances 1-4 antiradical activity according to their ability to interact with the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH •). It was found that all synthesized compounds 1-4 have antiradical activity. Pronounced antiradical activity was shown by Nethyl-2-(2-hydroxybenzoyl)hydrazine-carbothioamide (1) (IC50(DPPH) = 12.5 µМ) and N-ethyl-2-(4-hydroxybenzoyl)hydrazine-carbothioamide (2) (IC50(DPPH) = 16.7 µМ) samples under the conditions of this test system. Activity of N-ethyl-2-(2-hydroxybenzoyl) hydrazinecarbothioamide (1) and N-ethyl-2-(4-hydroxybenzoyl)hydrazinecarbothioamide (2) samples are comparable to activity of known antioxidants. Studied substances 1 and 2 are promising for further advanced research of their antioxidant properties and other types of biological activity. Results of PASS computer system applicability estimation for prediction of biological activity using structural formula as a part of pre-experimental screening are provided. Expected activity of chemical compounds combines physiological activity of initial hydrazides of o-and p-hydroxybenzoic acids as well as components of structural molecule. According to bioprediction data analysis, all compounds can act as inhibitors with a high degree of probability.

show abstract

“…Therefore, a comprehensive understanding of the properties of ligands and metal complexes may result in the synthesis of highly active compounds. The most important advantages of using Schiff base ligands in metal complexes are that they include the hydrogenation of olefins and carbonyl groups, the transfer of an amino group and their capability to form complexes against toxic metals and other applications [6][7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Preparation and spectroscopic studies of Fe(II), Ru(II), Pd(II) and Zn(II) complexes of Schiff base containing terephthalaldehyde and their transfer hydrogenation and Suzuki-Miyaura coupling reaction

et al. 2019

Self Cite

View full text Add to dashboard Cite

This study describes synthesis, spectroscopic characterization and catalytic activities of Fe(II), Ru(II), Pd(II) and Zn(II) complexes with a novel Schiff base ligand (L) derived from methyl 2-amino-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate and terephthalaldehyde. We used spectroscopic techniques including IR, UV-Vis, 1H-NMR, 13C-NMR, elemental analysis and also mass analysis and magnetic susceptibility measurements to identify the products. The Pd(II) complex was used as a potential catalyst for Suzuki-Miyaura coupling reaction of some aryl halides under optimized conditions. The effect of various bases such as NaOH, KOH, and KOBut was investigated in transfer hydrogenation (TH) of ketones by isopropyl alcohol as the hydrogen source. Ru(II) and Pd(II) complexes showed catalytic activity while Zn(II) and Fe(II) metal complexes failed to do that.

show abstract

Synthesis, structural characterization and biological activities of metal(II) complexes with Schiff bases derived from 5-bromosalicylaldehyde: Ru(II) complexes transfer hydrogenation

Cited by 65 publications

References 46 publications

Developments in Platinum-Group Metals as Dual Antibacterial and Anticancer Agents

Developments in Platinum-Group Metals as Dual Antibacterial and Anticancer Agents

Antiradical activity and bioprediction of o-and p-hydroxybenzoic acid hydrazide derivatives

Preparation and spectroscopic studies of Fe(II), Ru(II), Pd(II) and Zn(II) complexes of Schiff base containing terephthalaldehyde and their transfer hydrogenation and Suzuki-Miyaura coupling reaction

Contact Info

Product

Resources

About