Synthesis, structure and antimicrobial evaluation of new 3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl-thiazol-4(5H)-ones

Efficient MW-Assisted Synthesis, Spectroscopic Characterization, X-ray and Antioxidant Properties of Indazole Derivatives

“…Tetrahydroindazole are potent medicinal scaffolds and exhibt a full spectrum of biological activities [13][14][15][16][17]. Due to their attractive pharmacological properties tetrahydroindazole derivatives have attracted the attention of chemists who have researched ways to obtain the desired properties through different synthetic strategies [18].…”

Ultrasound‐Assisted Facile Synthesis and Antimicrobial Studies of Alkanediyl‐bis‐thiazolidin‐4‐ones and Alkanediyl‐bis‐thiazinan‐4‐ones

“…) showed potent inhibitory activity against chikenguniya virus . In continuation to our studies on various synthesis pathways of thiazolidin‐4‐one derivatives , we report here ultrasound‐assisted efficient synthesis method and subsequent antimicrobial studies of some alkanediyl‐bis‐2‐arylthiazolidin‐4‐ones and alkanediyl‐bis‐2‐aryl‐1,3‐thiazinan‐4‐one derivatives.…”

“…The synthesized compounds alkanediyl‐bis‐2‐arylthiazolin‐4‐ones 2 and alkanediyl‐bis‐2‐aryl‐1,3‐thiazinan‐4‐ones 3 (Scheme ) were assayed against bacteria and fungi stains by the method reported in our earlier communication . The minimum inhibitory concentration (MIC) values in μg/mL have been reported in Table .…”

Crystal structure of 2-[(3aS,6R)-3,3,6-trimethyl-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl]thiazol-4(5H)-one

“…linked to an N atom of a pyrazole ring, similar to the situation in the title compound, yielded six hits. One of these structures, 2-(3-phenyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl)-1,3thiazol-4(5H)-one (refcode LUHGAY; Gautam & Chaudhary, 2015), resembles the title compound with an indazole ring system linked to a thiazole ring. The mean plane of the two five-membered rings are inclined to one another by ca 10.05 , similar to the arrangement in molecule A of the title compound.…”