Synthesis, structure and biological activity of cobalt(II) and copper(II) complexes of valine-derived schiff bases

Lv, Jian; Liu, Tingting; Cai, Sulan; Wang, Xin; Liu, Lei; Wang, Yongmei

doi:10.1016/j.jinorgbio.2006.07.014

Cited by 154 publications

(75 citation statements)

References 44 publications

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“…[2][3][4]. And also, their metal complexes often exhibit antibacterial, antiviral, fungicidal or antitubarculoral activity [5,6]. In the title compound, C17H 12 N 2 O 3 , the naphthalen and phenyl ring groups are planar with an r.m.s.…”

Section: Discussionmentioning

confidence: 99%

Crystal structure of (E)-3-((naphthalen-1-ylimino)methyl)-4-nitrophenol, C₁₇H₁₂N₂O₃

Bülbül

Köysal

Macit

et al. 2016

Zeitschrift Für Kristallographie - New Crystal Structures

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CCDC no.: 1484947The asymmetric unit of the title crystal structure is shown in the figure. Tables 1 and 2 contain details on crystal structure and measurement conditions and a list of the atoms including atomic coordinates and displacement parameters. Source of material(E)-3-((naphthalen-1-ylimino)methyl)-4-nitrophenol was prepared by refluxing a mixture of a solution containing 5-hydroxy-2-nitro-benzaldehyde (8.4 mg, 0.05 mmol) in

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Section: Discussionmentioning

confidence: 99%

Crystal structure of (E)-3-((naphthalen-1-ylimino)methyl)-4-nitrophenol, C₁₇H₁₂N₂O₃

Bülbül

Köysal

Macit

et al. 2016

Zeitschrift Für Kristallographie - New Crystal Structures

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“…Among the various β-diketones, curcumin is a versatile compound as their traditional consequence in medicinal field [10][11][12][13][14][15][16][17]. A search through literature reveals that more have been posted on the studies of Schiff bases [18][19][20]. But, there is no research articles accounted on the synthesis of macrocyclic Schiff base first row transition metal complexes using benzalidene-curcuminyl-4-iminoantipyrine with 2,6-diaminopyridine [21][22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, Antimicrobial and Anticancer Activities of 14-Membered Macrocyclic Schiff Base Metal Complexes

Palanimurugan¹,

Kulandaisamy²

2018

Asian J. Chem.

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New cationic 14-membered macrocyclic Schiff base metal complexes have been synthesized by condensation of benzalidene-curcuminyl-4-iminoantipyrine and 2,6-diaminopyridine. Structural characterization of the compounds was done using elemental analysis, molar conductivity, magnetic susceptibility, Mass, SEM, XRD, 1 H NMR, UV-visible, IR and EPR spectra. X-ray diffraction patterns suggested that the size of Schiff base is reduced due to chelation by the metal ion. Different morphologies of synthesized compounds were identified by SEM images. Magnetic moment values, UV-visible and IR spectral studies confirms the square planar geometry of chelates. However [VOL]Cl2 exists in octahedral geometry. Electron spin resonance spectra parameters of [CuL]Cl2 and [VOL]Cl2 complexes were well coinciding with proposed geometries. The in vitro biocidal activities of the compounds were done against some bacterial and fungal strains by disc diffusion method. Anticancer activity of Schiff base and copper complex were carried out by MTT method which reveals that the inhibition against the growth of breast cancer cell line culture for chelate is higher than Schiff base.

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“…Transition metal complexes of Schiff bases have attracted a lot of interest due to their potent biological activities such as antifungal, antibacterial, anticancer and herbicidal applications [12][13][14][15][16]. These studies have shown that 0020-1693/$ -see front matter Ó 2010 Elsevier B.V. All rights reserved.…”

Section: Introductionmentioning

confidence: 99%

Anticancer and antifungal activity of copper(II) complexes of quinolin-2(1H)-one-derived Schiff bases

Creaven

Duff

Egan

et al. 2010

Inorganica Chimica Acta

207

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a b s t r a c tThe condensation of substituted aromatic aldehydes with 7-amino-4-methyl-quinolin-2(1H)-one (1) has lead to the isolation of quinolin-2(1H)-one derived Schiff bases (2-14). The copper(II) complexes (2a-14a) of the ligands were also prepared, and together with their corresponding free ligands were fully characterised by elemental analyses, spectral methods (IR, 1 H and 13 C NMR, AAS, UV-Vis), magnetic and conductance measurements. The bidentate ligands coordinated to the copper(II) ion through the deprotonated phenolic oxygen and the azomethine nitrogen of the ligands in almost all cases. X-ray crystal structures of two of the complexes, 5a and 8a, confirmed the bidentate coordination mode. All of the compounds were investigated for their antimicrobial activities against the fungus, Candida albicans, and against Gram-positive and Gram-negative bacteria. The compounds were found to have excellent antiCandida activity but were inactive against Staphylococcus aureus and Escherichia coli. Selected compounds (2-8 and 2a-8a) were also screened for their in vitro anticancer potential using the human hepatic carcinoma cell line, Hep-G 2 . Several derivatives were shown to be active comparable to that of cisplatin.

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Synthesis, structure and biological activity of cobalt(II) and copper(II) complexes of valine-derived schiff bases

Cited by 154 publications

References 44 publications

Crystal structure of (E)-3-((naphthalen-1-ylimino)methyl)-4-nitrophenol, C₁₇H₁₂N₂O₃

Crystal structure of (E)-3-((naphthalen-1-ylimino)methyl)-4-nitrophenol, C₁₇H₁₂N₂O₃

Synthesis, Characterization, Antimicrobial and Anticancer Activities of 14-Membered Macrocyclic Schiff Base Metal Complexes

Anticancer and antifungal activity of copper(II) complexes of quinolin-2(1H)-one-derived Schiff bases

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Synthesis, structure and biological activity of cobalt(II) and copper(II) complexes of valine-derived schiff bases

Cited by 154 publications

References 44 publications

Crystal structure of (E)-3-((naphthalen-1-ylimino)methyl)-4-nitrophenol, C17H12N2O3

Crystal structure of (E)-3-((naphthalen-1-ylimino)methyl)-4-nitrophenol, C17H12N2O3

Synthesis, Characterization, Antimicrobial and Anticancer Activities of 14-Membered Macrocyclic Schiff Base Metal Complexes

Anticancer and antifungal activity of copper(II) complexes of quinolin-2(1H)-one-derived Schiff bases

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Crystal structure of (E)-3-((naphthalen-1-ylimino)methyl)-4-nitrophenol, C₁₇H₁₂N₂O₃

Crystal structure of (E)-3-((naphthalen-1-ylimino)methyl)-4-nitrophenol, C₁₇H₁₂N₂O₃